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3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

A user's progress with treating hair loss by using finasteride (1mg MWF) and minoxidil (5% once daily), occasionally using ketoconazole gel, and dermarolling 1.5mm every two weeks; other users' responses are positive and ask for more information about the treatment regimen.

People discussed using vitamin D supplements for hair loss, with some also using steroid injections, pumpkin seed oil, saw palmetto, and zinc. Despite supplementation, one user noted no improvement in hair condition, but acknowledged the general health benefits of addressing vitamin D deficiency.

A new company is introducing a topical treatment combining Minoxidil, Finasteride, and Bimatoprost for hair loss. Users are also inquiring about updates on a minoxidil-enhancing shampoo from Applied Biology.

The user switched from finasteride to 0.5mg oral dutasteride and added 2.5mg oral minoxidil, along with occasional microneedling, to improve hair regrowth. They reported no side effects and are hopeful for continued progress, especially in the temple area.

A 19-year-old is experiencing diffuse thinning and has been on finasteride for 6 months, noticing a slower but still concerning rate of hair loss. They started taking 0.5mg of dutasteride once a week in addition to 1.25mg of finasteride on other days and are seeking advice on this treatment approach.

The conversation discusses the potential offering of oral finasteride/dutasteride and oral minoxidil treatments for hair loss, with feedback on pricing and preferences for separate or combined pills. Users express concerns about high costs, preferring affordable options, and some prefer oral over sublingual minoxidil for ease of use.

A 20-year-old diffuse thinner has been using finasteride for 8 months and is considering adding minoxidil to their routine. A user suggests incorporating minoxidil for quicker regrowth, despite the hassle of daily application, while continuing finasteride.

The user has been applying 2ml of 5% minoxidil and 0.1% topical finasteride daily for hair loss and started derma rolling a week ago. They are considering adding 0.025% topical dutasteride to their routine twice a week and are seeking advice.

A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

The user is experiencing hair regrowth using a combination of oral finasteride, a minoxidil/finasteride topical spray, and dermarolling. They plan to continue this regimen and may consider adding dutasteride if needed.

The conversation discusses the potential use of HMI 115 for hair loss and whether it could replace or be used alongside finasteride, minoxidil, and RU58841. The user is experiencing scalp inflammation and continued hair shedding despite using finasteride for 8 years.

A 19-year-old is experiencing hair regrowth using 0.5mg dutasteride, topical minoxidil at night, topical redensyl in the morning, and weekly dermarolling. They have been on the treatment for a month and plan to share monthly updates over the next two years.

A user found a successful hair loss treatment using a combination of finasteride, dutasteride, minoxidil, and RU58841. They plan to switch to a purely topical regimen with finasteride, RU58841, and minoxidil.

A 20-year-old male is experiencing worsening diffuse thinning despite using topical minoxidil, topical finasteride with minoxidil, oral finasteride, stemoxydine, and pyrilutimide. He is seeking support and advice as he struggles with the mental and physical challenges of hair loss treatments.

Applying hair loss treatments like minoxidil and finasteride, with concerns about side effects and application timing. Some users experience side effects, while others manage without issues, and there's interest in future treatments like pyrilutamide.

A 33-year-old male has been using topical dutasteride and minoxidil twice daily, along with a 0.25 mm derma roller every five days, and is experiencing hair shedding but seeing progress. Some users suspect a hair transplant, while others praise the results.

The user has been treating hair loss with finasteride, minoxidil, microneedling, Nizoral shampoo, and Nutrafol, and is asking for opinions on their progress. Suggestions include continuing current treatments, considering dutasteride or other options, and being cautious with microneedling frequency to avoid scar tissue.

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

The user experienced significant hair regrowth using topical finasteride/minoxidil and oral minoxidil/dutasteride, with some mild side effects that diminished over time. They plan to add microneedling to their regimen and have seen hair shedding cycles every six months, followed by thicker regrowth.

A user shared their positive experience with the telehealth service DocBright, highlighting its affordability and effectiveness in prescribing finasteride, oral minoxidil, and ketoconazole. They noted the service's unique ability to provide a prescription at age 17 but criticized the unprofessional communication with the dermatologist.

A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

The user started a hair loss treatment with oral finasteride, minoxidil, and microneedling but hasn't seen improvement after six months, experiencing increased shedding instead. Suggestions include continuing the treatment for a year, considering topical minoxidil, and possibly adding dutasteride if needed.

Dutasteride mesotherapy, combined with peptides and exosomes, is being considered for hair loss treatment. One user suggests that oral finasteride or dutasteride mesotherapy may not be necessary if already taking oral dutasteride.

A 21-year-old is using a topical solution with minoxidil and finasteride for hair loss, along with supplements and specific shampoos, and is considering switching to oral treatments if no progress is seen in a few months. They are concerned about diffuse thinning and potential future hair transplants, and are exploring additional treatments like microneedling and tretinoin.

The user is using Minoxidil, Finasteride, microneedling, and plans to add low-level laser therapy (LLLT) to treat hair thinning. They shared progress pictures showing results from May 8th to June 7th.

A user started taking finasteride 1mg/day for hair loss but hasn't seen results yet. They also take vitamins and asked about adding minoxidil and the effectiveness of LLLT.

The user is using a hair loss treatment regimen including Avodart (dutasteride), oral minoxidil, LLLT caps, vitamins, and ketoconazole shampoo, and is considering adding dermarolling and RU58841. They are experiencing unwanted body hair growth from minoxidil and are planning for a future hair transplant.

The user started using Hims Finasteride and Minoxidil topical in July 2023, added daily microneedling in November, and switched to chewable Finasteride and Minoxidil in January with increased microneedling frequency. They observed hair regrowth, suggesting diffuse thinning may be easier to treat.

An individual is seeking options for topical finasteride and minoxidil in Australia, considering products from Medicii Labs and exploring other suppliers. They plan to use a derma roller and caffeine + yerba mate hair wash alongside these treatments.