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      community PP405 Phase 2a press release with early results

      in Research/Science  696 upvotes 10 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community How effective is a 7% MNX 0.1% FNS topical?

      in Product  1 upvotes 3 years ago
      A user discusses their rapidly receding hairline and a prescribed topical solution containing 7% Minoxidil, 0.1% Finasteride, and 3% biotinoyl tripeptide. The solution is a custom compound from their dermatologist, costing $50 for a one-month supply.

      community Progress photo shy of 1.5 years

      in Progress Pictures  14 upvotes 1 year ago
      User shared a progress photo after 1.5 years of using 1mg Finasteride daily, 5% Minoxidil twice daily, Nizoral shampoo and conditioner 2-3 times weekly, and derma stamping bi-weekly. The post is categorized under "Progress Pictures."

      community Microneedling doesnt seem to do anything

      in Microneedling  6 upvotes 2 years ago
      The user has been using finasteride for 2 years, nizoral for 1.5 years, topical minoxidil for 1 year, and microneedling for 3 months to treat hair loss but hasn't seen improvement or regrowth, even experiencing shedding with new treatments. They are concerned about continued thinning despite the treatments.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

      community 17-Month Update - Dut, Min, Niz, 1.5mm roller.

      in Progress Pictures  313 upvotes 2 years ago
      A 39-year-old shared a 17-month hair loss treatment update using Dutasteride, Minoxidil, Nizoral shampoo, and a 1.5mm derma roller, noticing significant results after 9-12 months. They also maintain a healthy lifestyle and manage side effects like dry skin with moisturizer.

      community Sulfate in Nizoral vs. Head & Shoulders

      in Ketoconazole 6 years ago
      The conversation discusses the presence of sulfates in Nizoral and Head & Shoulders shampoos. The user seeks advice on whether to return Head & Shoulders for a sulfate-free alternative and recommendations for a second shampoo/conditioner to alternate with Nizoral.

      community Fin + Min + Niz + Microneedling

      in Is this regrowth?  18 upvotes 2 years ago
      The conversation discusses hair regrowth using finasteride, minoxidil, ketoconazole shampoo (Nizoral), and microneedling as treatments. Users are sharing their experiences and results with these specific hair loss treatments.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  194 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community NW3 > NW1: DUT and microneedling only

      in Progress Pictures  789 upvotes 4 years ago
      User Topher1999 achieved hair regrowth using Dutasteride 3 times a week and microneedling with Dr. Pen Ultima A6 every 2 weeks for 9 months. They believe microneedling is the main reason for hairline gains.

      community Two of the most attractive girls I know are with NW7 guys

      in Chat  319 upvotes 10 months ago
      Bald men can still attract partners, as personality and confidence often outweigh hair loss. Treatments like finasteride and minoxidil are used, but self-acceptance and personal satisfaction are key.

      community Update: 14 months - NW Picard Progress

      in Progress Pictures  153 upvotes 4 months ago
      The user shared their hair regrowth progress using a combination of treatments including finasteride, dutasteride, minoxidil, tretinoin, Sulfogenz, KX-826, low-level laser therapy, and microneedling. They plan to continue medication for another year before considering a hair transplant, noting steady improvement but not major changes.

      community microneedling efficacy for male pattern baldness?

      in Microneedling  14 upvotes 1 week ago
      Microneedling, when combined with finasteride and topical minoxidil, can enhance hair regrowth for male pattern baldness, especially at the temples. Users report varying success with needle depths between 0.5mm and 1.5mm, with stamps preferred over rollers to minimize scalp damage.

      community Any other non-responders to most medications?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 2 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  247 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community GT20029 - Promising phase II results

      in Research/Science  16 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community What is next for pp405 in phase 2b?

      in Research/Science  16 upvotes 10 months ago
      PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 10 months ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.