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      community Still shedding after 6 months (2nd shed).

      in Treatment  4 upvotes 1 year ago
      The user is experiencing prolonged hair shedding despite using 1mg finasteride, 2.5mg minoxidil, and considering adding topical finasteride. They are also deficient in Vitamin D and B, and are exploring if supplements or dosage adjustments could help.

      community Rate my routine? Just started 21y/o

      in Product 8 months ago
      A 21-year-old has started a hair loss routine using topical finasteride and minoxidil, Nioxin stage 4 products, and supplements like biotin. They are considering adding oral minoxidil but are advised to wait and see results first.

      community Min Non responder. Tretinoin to become responder?

      in Minoxidil  2 upvotes 5 months ago
      The user did not respond to minoxidil and is considering using tretinoin to improve results. They also explored finasteride, microneedling, adapalene, red light therapy, and oral minoxidil as potential treatments.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  4 upvotes 6 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Balding at a young age - Hair loss Journey & Resolution

      in Hair Systems  21 upvotes 2 years ago
      A young individual experienced early hair loss and tried various treatments including Minoxidil, RU58841, micro-needling, and topical finasteride, which stopped the hair loss but did not regrow hair. Ultimately, they found a solution in a hair system, which restored their confidence and allowed them to participate in social activities again.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community Can anyone tell me what kind of issue this looks like?

      in Transgender  1 upvotes 2 years ago
      The individual is experiencing hair thinning primarily at the front/middle of their scalp and is seeking to identify the type of hair loss they have. They already use treatments like oral Minoxidil, topical Finasteride, Tretinoin gel, dermarolling, and various oils and shampoos.

      community Will I be a good candidate for Finasteride?

      in Chat 5 years ago
      A 17-year-old is considering finasteride for hair loss but is advised to wait due to potential hormonal effects at a young age. Alternatives like minoxidil, micro-needling, vitamins, and lifestyle changes are suggested instead.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 1 month ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  61 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Baby hair growth from non existent to existing.

      in Progress Pictures  173 upvotes 7 months ago
      A user shared progress pictures showing hair regrowth after using minoxidil and finasteride for several months. Despite skepticism, the user reports noticeable improvement and aims to motivate others with hair loss.

      community fin-min-keto-derma did not work for me. 24 yo

      in Update  16 upvotes 1 year ago
      A 24-year-old tried minoxidil, finasteride, keto shampoo, and derma-rolling for hair loss but saw no improvement and is now at Norwood 5. They feel there's nothing more they can do and are considering going bald despite not liking the look.

      community 18M- doctor surprised to see how I am still able to move

      in Treatment  27 upvotes 3 months ago
      The conversation discusses hair thinning and the potential role of vitamin D deficiency in hair loss, with suggestions to take vitamin D3 supplements. The user also mentions having diffuse thinning and a slightly receding hairline.

      community Zero Progress on dutasteride :(

      in Finasteride/Dutasteride  60 upvotes 2 weeks ago
      The user is frustrated with minimal hair regrowth after using dutasteride, oral minoxidil, and previously finasteride and topical minoxidil. Despite feeling discouraged, others suggest continuing treatment as progress can be slow and subtle, with some users noting visible improvement.

      community PP405 - hair stem cell stimulation

      in Research/Science  51 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community A little optimism post to detract from all the doom posting.

      in Technology  11 upvotes 3 weeks ago
      A user shares optimism about combating male pattern baldness using oral and topical minoxidil, highlighting the advancements in treatments available today. Another user agrees, noting that early treatment can yield good results, and mentions the availability of affordable hair transplants.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community Insane regression after hyper-responding (17M) AMA

      in Progress Pictures  137 upvotes 1 year ago
      A 17-year-old experienced significant hair loss after switching from topical to oral minoxidil and adding finasteride. The recommendation is to return to topical minoxidil and continue with finasteride or consider dutasteride.

      community never give up (19 to 21 years old)

      in Progress Pictures  281 upvotes 7 months ago
      The conversation is about a person recovering from drug-induced malnourishment, regaining hair growth, and improving overall health. They attribute their progress to stopping drug use, focusing on nutrition, and possibly using hormone replacement therapy (HRT).

      community HMI-115 question about potential earliest access

      in Research/Science  8 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.
      [19M] Am i too late for treatment?

      community [19M] Am i too late for treatment?

      in General  71 upvotes 11 months ago
      A 19-year-old started treating male pattern baldness with topical minoxidil, finasteride tablets, microneedling, and is considering PRP injections. They are concerned about the effectiveness and timing of these treatments.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  47 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.