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      Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

      community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

      in Research  413 upvotes 1 year ago
      Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  247 upvotes 3 years ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community I just don’t understand this

      in Finasteride/Dutasteride  115 upvotes 5 years ago
      Finasteride is discussed for hair loss treatment, with opinions divided on its safety and effectiveness. Some consider natural remedies, but these may also affect hormones.

      community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

      in Treatment  87 upvotes 6 years ago
      Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.
      Thinning in Hairline and Vertex - What do I do?

      community Thinning in Hairline and Vertex - What do I do?

      in General  345 upvotes 5 months ago
      A 25-year-old male is experiencing hair thinning at the hairline and vertex, considering using a dermapen or dermastamp, and seeking advice on whether to continue with natural remedies like onion juice and rosemary oil or start using minoxidil or finasteride. He is also looking for recommendations on microneedling devices.

      community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes

      in Progress Pictures  1031 upvotes 1 year ago
      The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.

      community 12 Months Hair Transplant Progress / 3500 Grafts (1 YEAR)

      in Transplants  1117 upvotes 1 year ago
      A user shared their 12-month progress after a 3500-graft hair transplant at Heva Clinic in Istanbul, choosing not to use minoxidil or finasteride. The results were praised, with comments noting the natural look and significant improvement.

      community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations

      in Research/Science  69 upvotes 5 years ago
      User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 4 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Flax seed gel?

      in Question  2 upvotes 7 years ago
      The conversation discusses using flax seed gel to control hair loss. Users also mention treatments like Minoxidil, finasteride, and RU58841.

      community Began An Intensive Protocol but it's now all habit.

      in Hair Systems  2 upvotes 4 years ago
      The user follows an intensive hair loss protocol including dutasteride, biotin, black tea, pumpkin seed oil, peppermint shampoo, rosemary conditioner, mukemame, soy milk, lycopene, garlic, magnesium, chamomile, spicy food, citrus bergamot, zinc, multivitamins, kefir, and Greek yogurt. They plan to alternate between pumpkin seed oil and safflower oil and will share before and after pictures.

      community isoflavones to combat gyno?

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      Isoflavones from soybeans may help limit estrogen's effects on the body, potentially preventing gyno. However, surgery is the only way to remove gland enlargement.

      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  53 upvotes 5 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

      community What's an anecdotal treatment you nevertheless swear by?

      in Product  11 upvotes 1 year ago
      Stemoxydine is highly recommended for hair loss, preferred over Minoxidil due to fewer side effects and dependency. The user also uses finasteride, Pur'ador shampoo, and suggests cold showers and spicy food as part of their routine.

      community M28, Surprising 20 day progress

      in Progress Pictures  4 upvotes 1 year ago
      A 28-year-old shared surprising hair regrowth progress after 20 days using topical minoxidil, micro needling, GHK-cu, and BPC-157 injections. The user noted a significant reduction in their bald spot and overall hair improvement.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 18M 8 months progress 40mg daily dut stack

      in Progress Pictures  112 upvotes 1 year ago
      An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

      community Expectations control for SCUBE3

      in Research/Science  21 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community Minoxidil scalp irritation, is there any solution?

      in Minoxidil  4 upvotes 6 years ago
      The conversation is about managing scalp irritation caused by minoxidil use. Suggestions include switching to foam, using fluocinonide topical solution, trying lipogaine for sensitive skin, and considering low-dose oral minoxidil.

      community How to reduce scalp DHT as much as possible?

      in Finasteride/Dutasteride  16 upvotes 7 months ago
      The conversation discusses reducing scalp DHT to prevent hair loss, with a focus on using dutasteride, finasteride, and other treatments like RU58841 and minoxidil. It highlights the challenges of managing hair loss while on high testosterone levels, suggesting that dutasteride may be more effective than finasteride in such cases.