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      community Losing hair. Dont know why and what to do

      in General  163 upvotes 1 year ago
      A 25-year-old is experiencing hair loss since 2022, possibly linked to post-COVID effects, and is hesitant to use minoxidil or finasteride due to side effects. They have tried shampoos, vitamins, and scalp massages with limited success and are seeking natural solutions.

      community Train your forehead and scalp muscles

      in Research/Science  23 upvotes 1 year ago
      Training scalp muscles to absorb more DHT is suggested as a hair loss solution, but users debate its effectiveness compared to medications like dutasteride and finasteride. Concerns about side effects of DHT blockers, such as reduced libido, are discussed, with some advocating for natural remedies like scalp massages and healthy living.

      community Turning vellus hairs into terminal hair

      in Research/Science  12 upvotes 1 year ago
      People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

      community I try without Fin. 6 month (1 year experience).

      in Is this regrowth?  16 upvotes 1 year ago
      The conversation discusses hair loss treatments, with the original poster using saw palmetto, biotin, minoxidil, a dermaroller, and rosemary oil, considering finasteride or a hair transplant in the future. Other users suggest finasteride or dutasteride for more effective results, while some recommend additional natural supplements and maintaining overall health.

      community DHT Blocker without Selenium and Zinc??

      in Female  6 upvotes 1 year ago
      A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using Saw Palmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Hair Regrowth , 2020-2024 , M26 Years

      in Progress Pictures  1112 upvotes 2 years ago
      A man shared his hair regrowth progress from 2020 to 2024 using finasteride, minoxidil, microneedling, and a good hair care routine. People reacted positively, asking about specific treatments and tools used, and he received compliments on his natural-looking results.

      community 1 year progress on fin/min with photos

      in Progress Pictures  9 upvotes 2 years ago
      A 27-year-old has been using oral finasteride and minoxidil since early 2023, seeing progress in hair growth and density without side effects, but still struggles with thinning at the crown. They are considering adding topical treatments, natural oils, microneedling, or a hair transplant to address this issue.