Search
for

    Sort by

    Community Join

    240-270 / 1000+ results

      community Breezula Phase 3 confusion - did they change something?

      in Chat  10 upvotes 5 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Fighting Seb Derm + MPB - Winning

      in Progress Pictures  74 upvotes 9 months ago
      The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.

      community Predicted Breezula format? (liquid/cream/foam etc)

      in Treatment  10 upvotes 6 years ago
      The conversation is about the potential format of Breezula, a hair loss treatment, and concerns that it might be greasy or sticky. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.

      community B5 (Pantothenic acid), B7 (Biotin), B12

      in Treatment  4 upvotes 2 years ago
      The conversation discusses the effects of B5 (Pantothenic acid), B7 (Biotin), and B12 on hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Breezula Phase 3 Results enough for maintenance?

      in Treatment  11 upvotes 1 month ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community New treatment? Minox + Bimatoprost

      in Treatment  6 upvotes 2 years ago
      A user discussed a new hair loss treatment combining 5% Minoxidil with Bimatoprost 0.3mg/ml, applied once daily. They referenced a study suggesting Bimatoprost may be more effective than Minoxidil.

      community Whatever happened to breezula?

      in Finasteride/Dutasteride  16 upvotes 11 months ago
      Breezula, a potential hair loss treatment, is still in trials with no recent updates on its release, while its acne version, Winlevi, is available but expensive. Users discuss the high cost of hair loss treatments and alternatives like Minoxidil and topical Finasteride.

      community M28 104 days on dut+min and cafune shampoo

      in Progress Pictures  156 upvotes 2 months ago
      A 28-year-old has been using oral dutasteride 0.5 mg, topical minoxidil 5%, and Cafune shampoo for 104 days with positive results and is considering adding microneedling. No side effects from dutasteride have been reported.

      community Clascoterone/ Breezula will it work

      in Research/Science 2 months ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

      community Anything stronger than DUT out there?

      in Finasteride/Dutasteride  14 upvotes 2 years ago
      The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

      community Lots of shedding after adding bica 50 mg daily

      in Transgender  119 upvotes 1 year ago
      Switching from spironolactone to bicalutamide caused severe hair shedding, despite using treatments like dutasteride, minoxidil, and estradiol injections. The user is experiencing androgenetic alopecia and is seeking solutions to stop the hair loss.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  19 upvotes 5 months ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

      community 30 M diffuse shining/bolding crown - stack

      in Treatment  2 upvotes 1 year ago
      A 30-year-old with diffuse thinning and a balding crown is using a treatment regimen of a 2-in-1 pill containing finasteride, minoxidil, and biotin, along with various supplements. After two weeks, no side effects have been experienced, and updates with pictures will be posted monthly.

      community Month 7. Dut/min/stemoxydine/microneedle. Nw7.

      in Progress Pictures  172 upvotes 1 year ago
      A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hair growth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.