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      community 6 months using topical, density looks alot better

      in Progress Pictures  126 upvotes 1 year ago
      A user shared progress pictures after 6 months of using a topical treatment with 6% Minoxidil and 0.3% Finasteride, showing improved hair density. Other users encouraged the progress and suggested adding a derma stamp for better results.
      Experiencing Short Prickly Hairs After 15 Months on Finasteride

      community Experiencing Short Prickly Hairs After 15 Months on Finasteride

      in General  90 upvotes 6 months ago
      The user has been using finasteride for over a year and noticed short, prickly hairs on their scalp that don't grow like the rest of their hair. Despite losing about 40 short hairs when washing, their overall hair density hasn't decreased.

      community Hair shed is driving me crazy/coping with stress

      in Female  11 upvotes 2 years ago
      A 25-year-old female is experiencing hair loss and has tried PRP, Minoxidil 5% with Biotin, and weekly needling sessions. Her doctor suggested switching to GFC treatment and stopping the needling sessions due to increased shedding, which may be caused by Minoxidil.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 1 year ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community how important is microneedling?

      in Finasteride/Dutasteride  17 upvotes 2 years ago
      User takes topical finasteride/minoxidil with little results, asks if microneedling helps for temple regions and if 0.5mm is enough. Replies suggest microneedling is effective and 0.5mm works, sharing personal regimens.

      community Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!

      in Treatment 3 years ago
      This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.

      community Got complimented on my hair today

      in Styling  46 upvotes 11 months ago
      The user experienced significant hair regrowth using a treatment of finasteride, minoxidil, tretinoin, and microneedling, reducing their Norwood scale from 2.5 to 1.5 in six months. They received compliments on their hair, boosting their confidence, and are now reducing their finasteride intake due to quick progress and potential side effects.

      community Microneedling and massaging scalp progress

      in Progress Pictures  7 upvotes 4 years ago
      A user shared their hair restoration journey using oral and topical finasteride, experiencing side effects with the former. They later switched to microneedling, scalp massages, and vitamins (D3, Zinc, Biotin, B complex, Vitamin E) with mixed feedback on progress.

      community Month 7. Dut/min/stemoxydine/microneedle. Nw7.

      in Progress Pictures  172 upvotes 1 year ago
      A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hair growth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.

      community 5 years – Fin, Min, Microneedle and then HT

      in Transplants  223 upvotes 3 years ago
      A user's experience of using Fin, Min and Microneedle treatments to help thicken their hair before undergoing a Hair Transplant (HT) procedure. The conversation also includes discussion about the results post-HT, including pictures.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  12 upvotes 1 year ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community 3 months on finasteride and hair density IS decreasing

      in Finasteride/Dutasteride  49 upvotes 2 weeks ago
      Finasteride can cause initial hair shedding as part of the treatment process, which is normal and often leads to regrowth of healthier hair. Users discuss experiencing multiple shedding phases and emphasize patience, as results can take several months to become noticeable.

      community Caffeine after dermarolling: Do or don't?

      in Treatment  3 upvotes 11 months ago
      Caffeine use after dermarolling is debated, with some users reporting positive effects on hair shedding and growth. One user recommends caffeine for reducing hair shedding and enhancing hair growth, while another is skeptical of its benefits.

      community 2 years on fin - hair recovery progress

      in Progress Pictures  277 upvotes 10 months ago
      A user shared their two-year progress using finasteride 1mg daily for hair recovery, noting significant improvement with minimal side effects like a slight decrease in libido. They initially tried microneedling weekly for six months but discontinued it, and they are now experimenting with reducing the finasteride dose to 0.5mg daily.

      community Starting 1mg Fin + 5% topical Min

      in Treatment  14 upvotes 1 year ago
      The conversation is about using 1mg finasteride and 5% topical minoxidil for hair loss, along with a dermaroller, Alpecin caffeine shampoo, and Nizoral shampoo. Users express optimism about the potential improvement in hair density.

      community Balding turned me into a Norwood mentalist

      in Chat  253 upvotes 2 years ago
      The conversation revolves around how balding has made the original poster and others hyper-aware of other men's hairlines, often judging the severity of their hair loss and whether they've had treatments like hair transplants, minoxidil, or finasteride. Some participants express a need for therapy due to their obsession, while others joke about their newfound "expertise" in assessing hair loss.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.