Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.
Monthly microneedling combined with low-dose topical dutasteride shows promising results for hair density and thickness with minimal side effects, especially in the frontal area. Despite its effectiveness, it is not widely discussed or used due to availability and cost concerns.
The user reports positive progress in hair growth using 0.25mg finasteride, minoxidil, ketoconazole shampoo, and microneedling, with minimal hair shedding and some new hair growth. They experienced decreased libido with finasteride but no longer have side effects from minoxidil.
The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.
A 35-year-old user shared their 4-month progress using Minoxidil, Finasteride, microneedling, and vitamins to treat hair thinning. They reported increased hair density, thicker strands, and deeper color, especially in the crown area.
Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.
The conversation discusses using TH16, a topical melatonin with resveratrol, and stemoxydine for hair maintenance, avoiding finasteride and minoxidil due to side effects. The user is considering a low-dose topical finasteride despite sensitivity.
The user shared progress in hair regrowth using a Minoxidil/finasteride topical compound and Olly Biotin. A suggestion to add microneedling was made, but a dermatologist said it's beneficial but not necessary.
User shared progress pictures showing significant hair improvement after using finasteride (0.25-0.5mg daily) for 11 months. Other treatments like microneedling, ketoconazole, and scalp massage were mentioned but not used consistently.
Exploring hair loss treatments, with a focus on Finasteride and RU58841 as well as other topical solutions like stemoxydine 5%. The user found that they were sensitive to both oral and topical finasteride, but remain optimistic about finding the right treatment.
The user has been using Minoxidil and finasteride for two years, which stopped their hair loss but did not regrow hair. They are inquiring if adding microneedling or tretinoin has provided benefits to others in similar situations.
The user shared progress pictures after using oral minoxidil 2.5mg, oral finasteride 0.25mg three times a week, and weekly 1.5mm microneedling for two months. They reported positive results in hair growth.
The conversation is about the use of microneedling, specifically with a derma stamp, for hair regrowth. Users discuss their experiences, pain levels, and the satisfaction of taking control over hair loss, with some mentioning the use of Minoxidil to enhance results.
The user experienced hair regrowth using finasteride every other day and topical minoxidil but is currently going through a shedding phase. Despite the shedding, progress is evident, and users suggest patience and possibly adding microneedling to improve results.
A user reports hair regrowth after 8 months using treatments including topical Minoxidil/Finasteride, microneedling, Nizoral shampoo, Pyrilutamide, GHK-Cu/Min topical, and supplements like fish collagen peptides, zinc, and vitamin D3. They've seen progress but slower regrowth in the midsection of the scalp and are seeking advice to improve it.
The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.
Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
The user is experiencing significant hair growth improvement after 5 months using finasteride, topical minoxidil, microneedling, and ketoconazole shampoo, with no side effects except less body hair. The routine includes daily oral finasteride, twice-daily topical minoxidil, weekly microneedling, and starting ketoconazole shampoo.
PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.
Stemson raised $15M for hair cloning, with hopes it becomes a reality in 10-20 years. Users are hopeful and discuss using Minoxidil and finasteride in the meantime.
The user experienced noticeable hair regrowth, especially at the hairline, after using Minoxidil, microneedling, vitamins, and specific shampoos for 2-3 months. They are considering adding finasteride but are hesitant due to potential side effects.
A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.
The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.
Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.
The user successfully reduced hair loss using pumpkin seed oil, Nizoral shampoo, and astaxanthin without using minoxidil or finasteride. They observed significant improvement over 12 months and believe the combination of treatments is effective.
Microneedling is considered an important addition to hair loss treatments like Finasteride, Minoxidil, and Nizoral, with evidence suggesting it enhances Minoxidil's effectiveness and can improve hair growth on its own. Users discuss various microneedling techniques, including heavy weekly sessions and lighter daily sessions, while expressing concerns about potential scalp damage and discomfort.
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
A 19-year-old shares positive results after one year on finasteride, minoxidil, micro-needling, and Nizoral shampoo, reporting no side effects and improved hair density despite initial shedding. Others discuss mixed experiences with finasteride, some considering alternatives like dutasteride or hair transplants.
Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.