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      community What can be the real reason of Finasteride SE ?

      in Finasteride/Dutasteride  19 upvotes 11 months ago
      Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

      community Dutasteride/finasteride theory

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      Finasteride worked better for frontal scalp hair loss, while dutasteride helped the crown and mid-scalp but worsened the frontal area. The user shared personal experiences and invited open dialogue.

      community Microneedling makes a difference. Non responders, please read

      in Microneedling  66 upvotes 2 years ago
      A 48-year-old who had been thinning since 25 and reached NW4-5 baldness saw no improvement with 1mg/day finasteride and 5% minoxidil twice a day after 8 months. After copying another person's routine, they now use 0.5mg finasteride, ketoconazole shampoo weekly, daily microneedling with 0.5mm and 1mm once a week, and apply minoxidil twice daily, resulting in baby hairs on their bald spot and temples after three months.

      community 7 months on from losing my mind

      in Chat  52 upvotes 1 month ago
      A 43-year-old man noticed hair thinning due to stress and started using Minoxidil, supplements, and specific shampoos, seeing improvement after 7 months. He is hesitant to add Finasteride due to fear of side effects but is managing stress better and feels more confident.

      community Microneedling at 1mm feels I'm hitting my skull

      in Microneedling  20 upvotes 1 year ago
      A user discusses their experience with at-home microneedling at 1mm for hair growth, feeling like they're hitting their skull. Other users suggest lowering the needle depth or stopping due to discomfort.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Has anyone tried Peptonix microneedling?

      in Product  4 upvotes 7 months ago
      The conversation discusses Peptonix microneedling, a copper peptide serum, as a potential hair loss treatment. Users compare it to finasteride and minoxidil, noting side effects and personal experiences with these treatments.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 3 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community How’s my pre fin lab work. Age 40

      in Chat  6 upvotes 2 years ago
      A user shared their pre-finasteride lab results, including DHT, estradiol, testosterone, SHBG, prolactin, FSH, and LH levels. Another user responded, cautioning against making unsupported claims about side effects and recovery.

      community Dutasteride and it’s effect on Erections

      in General  105 upvotes 1 year ago
      The user switched from finasteride to dutasteride and initially experienced increased energy and libido but is now facing erection issues. They are unsure if it's due to performance anxiety and are seeking advice while wanting to continue dutasteride for its benefits.

      community Not sure if fin+ deutasteride are working

      in Treatments  156 upvotes 1 year ago
      The user is concerned about hair loss despite using finasteride and dutasteride, with no regrowth but stabilized loss. After a recent hair transplant, they are experiencing shedding and are unsure if it's due to shock loss or ineffective treatment.

      community Don't think I can go on like this anymore

      in Chat  118 upvotes 7 months ago
      A 24-year-old is struggling with severe depression and anxiety due to hair loss, despite using dutasteride and oral minoxidil for two years. They are advised to consider shaving their head, exploring wigs or hair systems, and focusing on other aspects of life like health, relationships, and career.

      community Procapil - Has anyone heard of it?!

      in Research/Science  1 upvotes 3 years ago
      The conversation discusses Procapil, a treatment for hair loss containing Apigenin and Oleanolic acid. Users are sharing their experiences and asking if anyone has tried it.

      community Anyone tried Thicair? thoughts?

      in Product 10 months ago
      Thicair is a product combining microneedling and subdural vitamins for hair loss, containing ingredients like Panax Ginseng Root Extract and Copper Tripeptide-1. Users are skeptical, with one calling it "quackery."

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Anyone here who stopped microneedling and maintained or lost the gains?

      in Microneedling  9 upvotes 1 year ago
      Microneedling's long-term effects on hair loss are uncertain, with concerns about scarring and the need for continued use of minoxidil and finasteride to maintain gains. Finasteride does not sustain minoxidil-regrown hair without ongoing minoxidil use, and microneedling alone shows limited evidence of effectiveness.

      community PROGRESS ON NEW ROUTINE - DUT/Minox/Microneedling

      in Progress Pictures  6 upvotes 7 months ago
      The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.

      community Is this a regrowth or I’m just trippin?

      in Is this regrowth?  7 upvotes 3 months ago
      The user has been using 3mg oral minoxidil, 1mg finasteride, microneedling, and topical 5% minoxidil for hair loss. They are unsure about the results, noticing some regrowth but feeling dissatisfied overall.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community PP405: latest news. Really interesting

      in Research/Science  27 upvotes 3 months ago
      The conversation discusses impressive results from a 28-day application of a hair loss treatment. Users compare it to their experiences with Minoxidil and Dutasteride, noting excitement over the new findings.

      community Stopping finasteride for chemo

      in Finasteride/Dutasteride  108 upvotes 1 year ago
      A user diagnosed with lymphoma is advised to stop finasteride during chemotherapy, with suggestions to consider treatments like Dutasteride and Minoxidil post-recovery. The focus is on prioritizing health over hair loss, with encouragement and advice from others who have experienced similar situations.