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      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 8 months ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Not happy with current routine, suggestions for improvement?

      in Treatment  1 upvotes 4 years ago
      A 26-year-old male is unhappy with his current hair loss routine, which includes microneedling, ketoconazole shampoo, and a topical formula with Minoxidil, Finasteride, and other ingredients. He struggles with consistency due to ADHD and is considering switching to oral medication for simplicity, but is concerned about side effects and effectiveness.

      community Giving up on ever feeling comfortable in my body

      in Update  79 upvotes 4 years ago
      The user has been using finasteride, dutasteride, and RU58841 for hair loss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 2 years ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community Latanoprost shed - anyone have experience?

      in Treatment  4 upvotes 4 years ago
      The user started using topical latanoprost and dutasteride, experiencing significant hair shedding and scalp itchiness, possibly due to an allergic reaction. They are considering stopping the treatment if the shedding is linked to an allergy.

      community 8 week - sharing Finasteride blood test update

      in Progress Pictures  6 upvotes 2 years ago
      A 32-year-old male started taking 0.5mg of finasteride daily for hair thinning and, after 8 weeks, experienced a 70% reduction in DHT and an increase in estradiol; he is currently in the shedding phase of treatment and questioning if the dosage is correct based on his DHT levels. He began with a lower dose due to already low normal testosterone and DHT levels.

      community NW5.5 testing stack of most common "alternative" treatments and methods

      in Progress Pictures  2 upvotes 6 days ago
      A 43-year-old male with advanced hair loss is experimenting with alternative treatments, including red light therapy, microneedling, scalp massages, an oil mix, and ketoconazole shampoo, after previously experiencing side effects from finasteride and minoxidil. He noticed some minor changes with red light therapy but remains skeptical about significant improvement.

      community Interpreting pre-finisteride blood panels

      in Chat  2 upvotes 10 months ago
      The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.

      community Recommend stemoxydine as an adjunct therapy

      in Treatment  5 upvotes 2 years ago
      The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  164 upvotes 1 year ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

      community My DHT levels while being on DUT for a year

      in Finasteride/Dutasteride  34 upvotes 9 months ago
      The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.

      community UPDATE - 7 months 2,5 dutatesteride

      in Update  9 upvotes 10 months ago
      The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

      community Clascoterone phase 3 results are out!

      in Treatment  81 upvotes 4 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Interested about what other adjunct therapies people are trying & whats working?

      in Treatment  7 upvotes 2 years ago
      The conversation discusses alternative hair loss treatments beyond the commonly used Minoxidil and Finasteride. One user is trying diclofenac gel, caffeine + antioxidant serum, finasteride, ketoconazole shampoo, and has stopped using Minoxidil due to ineffectiveness, while another user has adopted lifestyle changes like exercise, diet, stress reduction, and topical caffeine, along with scalp massages and microneedling.

      community Where the fuck are the pyrilutamide GB guys?

      in Chat  23 upvotes 3 years ago
      The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

      community Topical Dutasteride - DHT Levels

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user reported using a topical hair loss treatment containing Minoxidil, Dutasteride, and other ingredients, noting a significant drop in DHT levels and a smaller decrease in testosterone after three months. They also mentioned microneedling, feeling fine with unchanged or increased libido, and taking Cialis as a preventative measure for performance issues.

      community People who used cyproterone for hair loss

      in Treatment  2 upvotes 2 years ago
      The conversation discusses the use of 12.5mg cyproterone every other day for hair loss. There's a concern about reducing testosterone potentially increasing DHT and negatively affecting hair.

      community 2026 Hairloss Nuclear Stack Update

      in Finasteride/Dutasteride  79 upvotes 1 month ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.