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      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 10 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  48 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community 4 months on fin/min/dermaroll/niz

      in Is this regrowth?  234 upvotes 3 years ago
      A 35-year-old who has been using topical and oral Minoxidil and Finasteride with dermarolling and Nizoral for four months, experiencing improved hair health but not yet full coverage on the crown. Others have responded encouragingly to this progress.

      community Hairline change after 1y3m on fin+min+microneedling

      in Progress Pictures  140 upvotes 2 years ago
      The user "Expliced" shared their progress pictures after using finasteride, minoxidil, and microneedling for 1 year and 3 months. Another user mentioned that using a high-definition camera with flash and sharpening the photo can show new hairs appearing sooner.

      community Anyone only on RU or Pyrilutamide?

      in Research/Science 1 year ago
      The conversation discusses using RU58841 or Pyrilutamide for hair loss, with some users suggesting switching to more proven treatments like oral or topical finasteride. One user reports no progress with RU58841, finasteride, and minoxidil, and mentions experiencing regression.

      community Weird response to microneedling

      in Microneedling  40 upvotes 1 year ago
      Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 3 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community Fin/Min/VitD 6 Month Progress Pics

       7 upvotes 7 years ago
      The user shared a 6-month update on their hair loss treatment using finasteride, minoxidil, Nizoral shampoo, and vitamin D. They reported progress but mentioned possible sexual side effects and recent shedding, seeking advice on adjusting their finasteride dose.

      community Anyone Taking CB-03-01

       7 upvotes 7 years ago
      The conversation is about someone seeking information on long-term users of CB-03-01 for hair loss, having experienced negative side effects from finasteride and facing rapid hair thinning.

      community 2 Year Fin/Min/Niz Journey AMA

      in Progress Pictures  1191 upvotes 2 years ago
      A user shared their 2-year hair loss treatment journey using 1mg finasteride daily, 2ml minoxidil daily, Nizoral shampoo 2-3 times a week, recently added dutasteride twice a week, and microneedling once a week. They've seen improvement in their hair and advise consistency with medication, with some users responding positively to the progress.

      community Opinion on my current progress

      in Is this regrowth?  6 upvotes 4 months ago
      The user is using 1 mg finasteride daily, Rogaine foam once a day, and Nizoral 2-3 times a week for hair regrowth. Progress is visible, but full effects of finasteride may take 12-18 months, and patience is advised.

      community 4 months 5% foam min + finasteride - 20 years old

      in Progress Pictures  57 upvotes 2 years ago
      A 20-year-old user experienced significant hair regrowth after using 5% minoxidil foam and finasteride for four months, starting to see results after two months with no side effects. They also cut off damaged hair ends, wash their hair every other day, and advise managing stress to improve hair loss outcomes.

      community I was scared of Fin. I now love it

      in Update  18 upvotes 2 years ago
      A 25-year-old male switched from multiple topicals to finasteride and minoxidil for hair loss, experiencing maintenance and increased confidence despite minor side effects. He now styles his hair freely and appreciates the positive impact of finasteride.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community [progress] Finasteride 42 MONTHS update

      in Update  66 upvotes 3 years ago
      The user's 42 month experience using finasteride for hair loss, their opinion on minoxidil use and the potential of pyrilutamide and another Chinese drug as treatments.

      community Post FUE finasteride - moved from oral to topical

      in Finasteride  90 upvotes 1 year ago
      The user switched from oral to topical finasteride with minoxidil after a hair transplant and is experiencing increased hair growth in unexpected areas like eyebrows and sideburns. They are seeking feedback from others with similar experiences.

      community 1+ year Nuclear Stack on 19M, AMA!

      in Update  112 upvotes 1 year ago
      A 19-year-old is using oral dutasteride, topical minoxidil, and dermastamping to address hair loss and enhance facial hair growth, experiencing minimal side effects and increased body hair. They report positive results in hairline thickness and temple closure.

      community Gonna start on Finasteride Tomorrow! 🤞

      in Chat  12 upvotes 2 years ago
      A 19-year-old male plans to start finasteride due to hair thinning after using creatine. He seeks advice on finasteride's effectiveness, especially for Asians.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.