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      community Olumiant active ingredient Baricitinib

      in Research/Science  1 upvotes 3 years ago
      The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  184 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community Anyone try RU58841 from this brand? truth진실

      in Product  5 upvotes 8 months ago
      The conversation discusses skepticism about the effectiveness and formulation of a $10 RU58841 gel from a Korean brand, questioning if ethanol is used to hold the active compounds. Concerns are raised about the feasibility of selling it at such a low price.

      community Balding since 2023, topical fin+keto+min since early 2025

      in General  118 upvotes 11 months ago
      The user is stressed about hair loss and is using a HIMS topical treatment containing finasteride, ketoconazole, minoxidil, and biotin, but is concerned about the oily appearance it causes. They are considering switching to Rogaine (minoxidil) due to budget constraints and side effect concerns with oral finasteride.

      community Nuclear topical fin formulation?

      in Chat  1 upvotes 8 months ago
      The conversation discusses a hair loss treatment involving oral minoxidil, topical finasteride, and a custom topical formulation with minoxidil, cetirizine, finasteride, progesterone, and hydrocortisone. The user seeks advice on the effectiveness of these ingredients for diffuse thinning.

      community Thoughts on Lactobacillus Reuteri 6475?

      in Treatment  3 upvotes 1 year ago
      Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

      community Could RU58841 actually worsen hairloss?

      in Treatment  2 upvotes 1 year ago
      The user experienced worsening hair density after using finasteride, dutasteride, and RU58841, suspecting RU58841 might be the cause. They are considering stopping RU58841 after a scalp biopsy, while others share mixed experiences with RU58841's effectiveness.

      community Does CosmeRNA target the root cause of MPB?

      in Chat 3 years ago
      . CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.

      community Diagnosed with MPB at 16 (Male)

      in Treatment  56 upvotes 2 years ago
      A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

      community 2 year progress with ( fin + min + keto)

      in Progress Pictures  80 upvotes 11 months ago
      The conversation is about a user's two-year hair loss treatment progress using 1mg oral finasteride daily, Kirkland minoxidil twice a day, and Nizoral 1% shampoo three times a week. The user reports no side effects and attributes most progress to finasteride and minoxidil.

      community Finasteride affects both 5a reductase and 5b reductase

       7 upvotes 6 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community Why do some people (specially those with diffuse balding) experience more regrowth just with DHT blockers?

      in Chat  41 upvotes 8 months ago
      Diffuse thinners often experience more hair regrowth with DHT blockers like finasteride, possibly due to less DHT sensitivity and the presence of miniaturized, not completely bald, follicles. However, regrowth varies widely among individuals, influenced by factors like genetics, the stage of hair loss, and treatment methods such as minoxidil, microneedling, and dermarolling.

      community I solved my scalp inflammation

      in Treatment  30 upvotes 2 years ago
      A user solved their 15-year scalp inflammation and related hair loss using Selenium Sulfide shampoo (Selsun Blue), noticing improvement after the first use and resolution after three uses. Others found relief with Ketoconazole shampoo, which also helps with hair loss.

      community Microneedling questions (18yo) on RU

      in Treatment  1 upvotes 3 months ago
      An 18-year-old is seeking advice on microneedling while using RU58841 for hair loss. Recommendations include using a derma pen with 0.5mm needles every two weeks and avoiding RU application for 24 hours post-microneedling to prevent absorption into the bloodstream.

      community Why are there no FDA approved NSAA's yet?

      in Research/Science 1 year ago
      The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Alright so FDA better approve PP405 as fast as they approved covid vaccine

      in Product  130 upvotes 9 months ago
      PP405 is a potential hair loss treatment showing promising early results, with hopes for market release by 2028, but skepticism remains due to inconclusive data and past disappointments with similar products. Current treatments like Minoxidil and Finasteride have side effects, leading some to anticipate PP405 as a safer alternative, though its effectiveness compared to placebo is debated.

      community What makes breezula different than formula 82f?

      in Question  9 upvotes 6 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.