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      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Best shampoo and conditioner for hair loss

      in Product  6 upvotes 2 years ago
      The user is using minoxidil, finasteride, Nizoral 2%, and microneedling for hair loss but finds Nizoral drying. They seek affordable shampoo and conditioner recommendations, with one reply suggesting baby shampoo for non-Nizoral days.

      community HMI-115 question about potential earliest access

      in Research/Science  10 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community Not happy with current routine, suggestions for improvement?

      in Treatment  1 upvotes 4 years ago
      A 26-year-old male is unhappy with his current hair loss routine, which includes microneedling, ketoconazole shampoo, and a topical formula with Minoxidil, Finasteride, and other ingredients. He struggles with consistency due to ADHD and is considering switching to oral medication for simplicity, but is concerned about side effects and effectiveness.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Stabilized hairloss without sides (finally)

      in Finasteride/Dutasteride  20 upvotes 3 years ago
      User found hair loss stabilization without side effects using a topical solution of 0.008% Finasteride, 2% RU, and Stemoxydine. Other treatments like Eucapil, Fluridil, RU-monotherapy, and Pyrilutamide didn't work for them.

      community Clascoterone phase 3 results are out!

      in Treatment  83 upvotes 6 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 2 years ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

      community Pyrilutamide vs Ru58841 thoughts

      in Research/Science  8 upvotes 3 years ago
      The user has been using Pyrilutamide (Pyril) for hair loss for a month alongside finasteride/dutasteride since 2021 but hasn't seen results. They are considering switching to RU58841 due to its many success stories, despite being skeptical about the legitimacy and testing of Pyrilutamide.

      community Crystals in Minoxidil bottle

      in General  89 upvotes 1 year ago
      Minoxidil bottle developed crystals, possibly due to air exposure, but the trichologist advised not to worry. The user questions the advice, noting the lack of recommendations for finasteride or derma rolling.

      community Second shed and more abnormalities

      in Treatment  1 upvotes 1 year ago
      The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

      community Why is nobody talking about topical Spironolactone?

      in Chat  12 upvotes 2 months ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

      community Do we have to be junkies? That's funny

      in Research/Science  12 upvotes 1 year ago
      The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

      community New Approach to Ketoconazole or just waste of time?

      in Ketoconazole  21 upvotes 2 years ago
      The post discusses using 2% ketoconazole shampoo as a competitive androgen receptor antagonist for hair loss, applied for 1.5 hours daily. The user questions its effectiveness and potential benefits compared to finasteride and minoxidil.

      community 14-month update - dut, min, niz, 1.5mm roller.

      in Progress Pictures  447 upvotes 2 years ago
      A user shared a 14-month hair loss treatment update using dutasteride, minoxidil foam, a 1.5mm derma roller, and Nizoral, with noticeable hair regrowth and no side effects. The discussion highlights the effectiveness of microneedling in combination with topical treatments, with many users agreeing it significantly enhances results.

      community 9-Month Routine Update. Advice?

      in Update  3 upvotes 2 months ago
      The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and has recently added microneedling, showing slight progress. The new protocol includes switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex, while seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

      community 24M seeking help for aggressive androgenetic alopecia - "nuke" stack?

      in Chat  1 upvotes 1 year ago
      A 24-year-old male with aggressive androgenetic alopecia is using 1mg finasteride daily and considering a treatment stack including 0.5mg dutasteride, 2.5mg oral minoxidil, ketoconazole shampoo, Alpecin caffeine shampoo, and RU58841. He seeks advice on the safety and effectiveness of these treatments and whether any adjustments are needed.

      community currently active protocols, working so far

      in Update 3 years ago
      The conversation is about a person's hair loss treatment routine, which includes Metformin, sleep in darkness, avoiding EMF at night, Nizoral, Dermarolling, Castor oil, and Collagen. They have observed less hair shedding and increased hair volume.