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      community P-1075: a BETTER version of Minoxidil

      in Research/Science 8 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Are these all the anti androgen products?

      in Treatment  6 upvotes 2 years ago
      The conversation lists hair loss treatments including finasteride, dutasteride, RU58841, pyrilutamide, breezula, and fluridil, and suggests ketoconazole as another option. Some users warn against using certain treatments like cyproterone acetate, bicalutamide, and spironolactone due to their strong anti-androgen effects and potential impact on masculinity.

      community Trying to eat Beetroot Powder and not get bald

      in Chat  7 upvotes 2 years ago
      The user is concerned about hair loss and is using minoxidil while considering beetroot powder, which may affect testosterone and DHT levels. They are cautious about starting finasteride due to potential side effects.

      community RootBioTec? Basil extract for hair growth

      in Product  4 upvotes 1 year ago
      RootBioTec, a basil hairy root extract, claims to reduce hair loss by 31% in two months by inhibiting 5α reductase II and stimulating hair follicles. There is limited independent information available about its effectiveness.

      community Verteporfin mixing solute for transplants

      in Treatment  12 upvotes 2 years ago
      Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

      community Warning: Danish Nordic Hair Growth is scam!

      in Product  86 upvotes 2 years ago
      A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenic alopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinical trial.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Any alternatives to topical min?

      in Treatment  1 upvotes 11 months ago
      The user is considering alternatives to topical minoxidil for hair growth due to concerns about future cat ownership, mentioning stemoxydine and redensyl as possibilities. They currently use topical regaine foam and oral finasteride.

      community Is it ok to supplement spearmint?

      in Treatment 6 years ago
      The conversation discusses the potential effects of spearmint on acne and male pattern baldness (MPB). Concerns are raised about spearmint's androgen-suppressing effects and its suitability for men.

      community Sea salt spray for thin, oily hair

      in Product  8 upvotes 1 year ago
      Sea salt spray is recommended for adding volume and managing oily, thin hair. It's affordable and effective, with store brands being a good option.

      community a topical that combines MIN, FIN and DUT

      in Minoxidil  5 upvotes 3 years ago
      A user discusses a topical treatment combining Minoxidil, Betamethasone Valerate, Canrenone, Finasteride, and Dutasteride for hair loss. The treatment is RX-only and provided by a dermatologist.

      community European release of clascoterone

      in Research/Science  13 upvotes 1 month ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 3 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  291 upvotes 5 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Taking part in a Clascoterone Study

      in Treatment  6 upvotes 2 years ago
      The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

      community Where to buy topical Adenosine?

      in Product  7 upvotes 3 years ago
      Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. User seeks where to buy topical Adenosine.

      community LPT: Sebhorric Detmatitis Treatment

      in Treatment  4 upvotes 8 years ago
      Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.

      community Reducing DHT levels naturally. Anyone getting good results?

      in Treatment  4 upvotes 2 years ago
      Natural alternatives like omega-3, green tea, and pumpkin seeds are suggested for reducing DHT levels, but their effectiveness is questioned. Topical minoxidil and ketoconazole shampoo are recommended, with some users also considering low-dose finasteride and saw palmetto.