The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.
A 16 year old's experience with using pyrilutamide to treat hair loss, and the potential side effects of adding tretinoin to minoxidil and finasteride treatments.
A user shared a list of natural supplements they tried that did not stop their male pattern baldness (MPB), including vitamin D, biotin, and various oils. The conversation includes skepticism and jokes about one of the methods, injecting jellyfish mucus into testicles, and mixed opinions on the effectiveness of natural treatments.
The conversation discusses a user's two-year hair regrowth progress using finasteride, minoxidil, and microneedling. One user asks for a timeline of progress, another comments on hair length, and the original poster mentions using microneedling sporadically.
A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.
The user has been using finasteride, minoxidil, microneedling, PRP, and ProCell therapy for hair loss but sees no progress after nine months. They are considering switching to dutasteride and possibly a hair transplant, with suggestions to add oral minoxidil.
A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.
User shared results of using minoxidil and dermaneedling for hair loss over 2.5 months, noting improvements, especially around the left temple. No finasteride or other anti-androgens were used.
Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.
OP has been using a premixed topical solution of 5% minoxidil and 0.025% tretinoin for 6 months with good results and is unsure if shaking the bottle is necessary. OP is also using Dutasteride and is curious about the impact of shaking on treatment effectiveness.