PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.
PP405 cannot restore extracted hair follicles after a transplant as they are removed, not dormant. Combining verteporphin with wounding and PP405 is suggested but not confirmed effective.
The user experienced hair growth using 5% topical Minoxidil foam twice daily from October 2024 to February 2025, without using finasteride due to family history of side effects. The user is considering other treatments like topical finasteride and received positive feedback on their progress.
The conversation discusses hair regrowth using finasteride, minoxidil, and a dermaroller. Users also talk about the benefits of using a stamp over a derma roller for scalp treatment.
Using tretinoin with minoxidil can cause burning and flaky skin due to alcohol in minoxidil and tretinoin's effects. Solutions include using minoxidil foam, starting with low tretinoin doses, moisturizing, and gradually increasing usage.
The user "Emotional_Fun4990" shared their progress after using 1mg Finasteride daily, 5% Minoxidil, and a 0.5mm Derma-roller twice a week for 2 months. They noticed additional hair growth below the hairline and on the neck. Other users provided positive comments and encouragement.
The user has seen positive results after over six months using 0.05% topical finasteride, 5% minoxidil, 50mg/ml RU58841, weekly needling, and twice-weekly ketoconazole shampoo for hair loss. They express gratitude for the support from an online community and are open to questions about their treatment.
The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.
An 18-year-old is using topical minoxidil 5% and derma rolling weekly for hair regrowth after shaving their head, while also addressing vitamin D deficiency and thyroid imbalance. They are questioning if the changes observed are signs of regrowth.
Microneedling is discussed as a method to improve hair growth, with users sharing their experiences and results using different needle depths and frequencies. Treatments mentioned include minoxidil, finasteride, rosemary oil, and saw palmetto supplements.
A user reported hair regrowth using a homemade topical solution of minoxidil and finasteride sourced from Pakistan, combined with microneedling, after experiencing hair loss with UK-based products. They claim a reduction in hair loss from 200-300 to 3-5 hairs a day and advise against spending money on branded products.
A hair restoration case involved injecting four different doses of Verteporfin into the mid scalp and using Scalp MicroPigmentation (SMP) around the extraction areas. Photos were taken and an update will be shared soon.
The user shared progress on hair loss treatment after one year on finasteride, with some use of microneedling, minoxidil, and ketoconazole. They plan to use microneedling with minoxidil more consistently for better results.
A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.
An experiment to determine the effectiveness of Pyrilutamide in reducing hair loss, using a regimen of Minoxidil and Finasteride, with promising results. The conversation also suggests comparing this to RU58841 as an alternative.
User harlital shared their 9-month hair loss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.
The user has been using topical minoxidil for 4 months and finasteride for 3 months, along with supplements and micro-needling, and is considering red light therapy for hair growth. They are seeking advice and support, discussing the potential switch to oral minoxidil due to convenience and concerns about side effects.
A user reported no improvement in hair loss after nearly a year of using 1mg oral finasteride, topical minoxidil twice daily, and weekly microneedling. Other users suggested the possibility of DUPA or retrograde alopecia and mentioned that treatments might only slow down hair loss rather than regrow hair.
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
The user has experienced limited hair regrowth using 1mg oral finasteride, topical minoxidil foam, and occasional dermarolling since August 2023. They are considering switching to dutasteride, adding oral minoxidil 2.5 mg, and RU58841 to improve results.
A user's progress with treating hair loss over 3.5 months, which involves taking finasteride MWF, minoxidil daily and microneedling once a week. There was positive feedback from other users regarding the results.
The conversation is about finding alfatradiol in the US for hair loss treatment. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.
User 765bonazoli asked about experiences with Minoxidilmax topical latanoprost for hair loss. No specific treatments were mentioned in the provided text.
The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.
The conversation discusses hair loss treatments, specifically using a Dermaroller, Minoxidil, and RU58841 for two months. The user shared progress pictures showing the results of these treatments.
The conversation discusses hair loss treatment progress using finasteride for 5 months and a topical solution with 0.1% minoxidil and 7% RU58841 for 11 months, with plans to switch to a stronger topical solution with 0.25% minoxidil, 7% RU58841, and tretinoin. Opinions on improvement are mixed.
Microneedling for hair loss involves sterilizing tools and possibly using serums like minoxidil or hyaluronic acid. Users report different routines, including applying minoxidil immediately after microneedling, using finasteride, and washing with ketoconazole shampoo.
Optimal microneedling routine is 1.25mm once a week with Dr Pen 36 needles. Applying Minoxidil right after microneedling may increase systemic absorption risk.
A user shared their experience with scalp micropigmentation (SMP) after one year. They discussed using Minoxidil, finasteride, and RU58841 as treatments for hair loss.
Minoxidil 5% foam was used twice daily for 4 months, resulting in visible hair regrowth. Users discussed adding finasteride for better long-term results, with concerns about its side effects and alternatives like breezula and clascoterone.