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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community I (diffuse thinner) would genuinely prefer having the Generic MPB hairloss

      in Chat  35 upvotes 1 year ago
      The conversation discusses struggles with diffuse thinning and hair loss treatments, including the use of dutasteride, minoxidil, and finasteride, with limited success. The original poster regrets having a hair transplant at 21 due to weak donor hair and ongoing thinning.

      community Spironolactone and pregnancy planning

      in Female  2 upvotes 11 months ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community 3 months minoxidil PO, finasteride PO, and biotin progress. 25M

      in Progress Pictures  493 upvotes 7 months ago
      A 25-year-old male shared his 3-month progress using oral minoxidil, finasteride, and biotin for hair growth, reporting positive results and minimal side effects, such as slightly reduced libido. He plans to continue treatment and possibly add microneedling, with hopes of further improvement and potential hair transplant if needed.

      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 1 month ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community Disappointing news on Breezula/CB-03-01

       18 upvotes 7 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  8 upvotes 6 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community M18, On tropical minox 5% for 2 months now

      in Minoxidil  27 upvotes 4 months ago
      An 18-year-old has been using 5% topical minoxidil for 2 months for hair loss, with a history of vitamin D deficiency and thyroid imbalance. Users suggest starting finasteride and blocking DHT for androgenetic alopecia (AGA).

      community 4 months progress at oral fin and oral minoxidil

      in Treatment  25 upvotes 1 year ago
      The user reported progress in hair growth after 4 months using 0.5 mg finasteride and 2.5 mg minoxidil daily, and is considering adding RU58841 to block DHT on the scalp. They experienced side effects like reduced libido and mild erectile dysfunction, and take supplements like zinc, iron, fish oil, vitamin D, magnesium, and vitamin E.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 11 months ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 3 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community 3 months on oral finasteride/minoxidil – early progress?

      in Progress Pictures  59 upvotes 4 months ago
      A 28-year-old male is documenting his early progress with oral finasteride (1mg daily) and oral minoxidil (2.5mg daily) for hair loss, noting some improvement after three months. He also uses supplements, head massages, and a derma roller, with no significant side effects reported.

      community Ulo low dose dut/fin hair serum

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      The user experienced severe sexual side effects from topical finasteride with minoxidil but found no side effects with low-dose dutasteride and finasteride serums from Ulo after a hair transplant. They also used a hair growth serum with saw palmetto without side effects.

      community Fin for 1 year+ no results, non-responder?

      in Finasteride/Dutasteride  10 upvotes 2 years ago
      A user has been on finasteride for over a year with minimal hair regrowth and is considering stopping it, despite no side effects. They are also planning a hair transplant and seeking additional hair growth treatments, while managing high testosterone and scalp issues like dandruff and oiliness.

      community Please be consistent and don't give up!

      in Is this regrowth?  418 upvotes 4 months ago
      A 29-year-old man regained his hairline using a consistent routine of topical minoxidil and finasteride, along with pumpkin seed oil, despite experiencing side effects like low libido and ED. He emphasizes the importance of consistency and is satisfied with his progress, choosing to avoid oral treatments due to potential side effects.

      community My personal experience/observations fighting AGA seriously for 5 years

      in Treatment  47 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

      community 24yo no progress 6 months fin + min

      in Progress Pictures  11 upvotes 3 months ago
      A 24-year-old has been using oral finasteride and topical minoxidil for six months with minimal progress in hair regrowth, despite starting derma rolling and considering telogen effluvium as a possible cause. Suggestions include switching to oral minoxidil, adding dutasteride, and continuing microneedling for better results.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 11 months ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community Dut for 8 months, getting crushed honestly

      in Update  43 upvotes 1 year ago
      The user has been using dutasteride, oral minoxidil, and vitamin D for 8 months with no improvement in hair loss. They are considering trying RU58841 or a hair transplant due to the ineffectiveness of current treatments.

      community 1 Year of Finasteride. 6 Months of Oral Minoxidil. Zero Results

      in Chat  6 upvotes 1 year ago
      A 25-year-old experiencing hair loss saw no improvement after one year of finasteride and six months of oral minoxidil, despite lifestyle changes. Suggestions included trying RU58841, increasing minoxidil dosage, and switching to dutasteride.

      community latanoprost for hairloss

       4 upvotes 7 years ago
      Exploring the potential of latanoprost as a hair loss treatment in combination with minoxidil and finasteride.

      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 2 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.