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780-810 / 1000+ resultscommunity Pyrilutamide binding affinity is similar to RU
Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.
community Minoxidil + Tretinoin + Fexofenadine?
The conversation discusses using Minoxidil with Tretinoin and Fexofenadine for hair loss. Some users doubt its effectiveness, noting Fexofenadine's unproven results for androgenetic alopecia.
community Could 0.1% of retinol be a good replacement for 0.01% tretinoin in combination with minoxidil?
The conversation discusses using 0.1% retinol as a potential substitute for 0.01% tretinoin with minoxidil for hair loss treatment. It mentions that tretinoin is not easily available in some countries, and retinol might be less effective but less harsh on the scalp.
community Clascoterone (Winlevi) Update for Canada
Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.
community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide
Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.
community M22. Does sebderm decrease effects of min and fin or I am simply fin and min nonresponder?
The user has been using minoxidil and finasteride for hair loss without positive results and switched to dutasteride 1.5 months ago. They suspect seborrheic dermatitis might be affecting the effectiveness of these treatments.
community The minoxidil product I brought only has ethanol and minoxidil in it and no other ingredients. Will this be absorbed into the scalp?
A minoxidil solution with only ethanol and minoxidil may not be properly absorbed without additional ingredients like propylene glycol or vegetable glycerin. It's suggested to use a reputable brand and test the product for authenticity.
community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders
Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.
community Red flags to watch out for when choosing a hair transplant clinic (from someone who worked in the industry)
Red flags to watch for when choosing a hair transplant clinic, such as high-pressure sales tactics, unclear surgeon assignments, and unrealistic promises. A user shared a positive experience with Skin Medics UK, highlighting transparency and personalized care.
community Topical fin formulation question
A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.
community 11 months oral miraclegro, 9 months topical roundup, 10 months spectracide, 6 months Cow Dung mesotherapy + weekly Foot stepping session
The conversation humorously discusses hair loss treatments, mentioning "oral miraclegro," "topical roundup," "spectracide," "Cow Dung mesotherapy," and "weekly Foot stepping sessions." The user jokingly considers switching to "weed and feed" as a treatment.
community What norwood is it? Don't sugarcoat it.
Minoxidil and finasteride might help with hair regrowth, but a hair transplant may be necessary for significant improvement. The conversation humorously discusses the severity of hair loss, comparing it to various exaggerated Norwood scale levels.
community NEW STUDY :why finasteride and dutasteride does not cause dry eyes
Finasteride and Dutasteride do not cause dry eyes by damaging meibomian glands, as these glands continue to function normally even when DHT is blocked. Some users report dry eyes with these medications, but others suggest supplements like Omega-3 or krill oil as potential remedies.
community The temporal peak - the often forgotten part in transplants?
Temporal peaks are crucial for a natural-looking hair transplant, but they are challenging to achieve due to the need for precise angles and appropriate hair thickness. Many users emphasize the importance of finding a skilled surgeon and using finasteride to maintain hairline stability.
community The only man in existence who actually looks better without hair, and has a NW0 into his 50s. Why is life like this?
Some men look better with shaved heads due to facial features and low body fat, while others believe a perfect hairline enhances attractiveness. Treatments like finasteride might be used to maintain a perfect hairline.
community Is my math correct? Mixing topical finasteride with stemoxydine to dilute the solution
The post discusses diluting 100ml of 0.1% topical finasteride with 90ml of stemoxydine to create a 0.05% solution, aiming for a longer-lasting and potentially less side-effect-prone treatment. The user seeks feedback on this idea.
community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
community Mild shedding after switching minoxidil formulations – coincidence or related?
Switching from liquid to foam minoxidil may cause mild shedding, possibly due to differences in absorption. Returning to the original liquid formulation typically stabilizes shedding within a few weeks.
community Genuine question about VDPHL01's long term safety that I haven't seen discussed here
Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.
community How do you guys apply min with an intensive skin care routine?
The conversation is about the order of applying minoxidil in a skincare routine, specifically whether to apply it before or after witch hazel and moisturizer. The user is concerned about the lotion interfering with minoxidil absorption.
community Ru vendor? Looking for a cheaper source
The conversation is about finding a cheaper source for RU58841, with a suggestion to use Chemyo. One user suggests that RU58841 may not be necessary.
community Haircafe video on Min Sulfate, thoughts?
Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.
community HMI-115: What We Know So Far. HMI-115 (also known as BAY1158061) is a new pharmaceutical drug developed by a biopharmaceutical company called Bioinvent and licensed by Bayer
HMI-115 is a new drug developed by Bioinvent and licensed by Bayer, with mixed opinions on its potential effectiveness. Some users are skeptical and prefer proven treatments like Minoxidil, finasteride, and RU58841.
community Tony Soprano before and after taking Minoxidil + Finasteride
Tony Soprano humorously imagined using Minoxidil and Finasteride for hair loss. Users joke about the character's potential treatments and his son's acting career.
community What are the chances of being chosen for PP405 trials?
The conversation discusses the potential benefits and risks of participating in the PP405 hair loss trials, emphasizing that those using Minoxidil or finasteride are less likely to be accepted. Participants are interested in the trial as it offers hope for effective treatment without the side effects associated with current medications.
community Has anybody done microneedling and NOT seen results?
The post discusses microneedling for hair regrowth, with the original poster seeking experiences of those who didn't see positive effects. A reply suggests that while microneedling doesn't guarantee hair regrowth, it increases the chances if done correctly.
community Tretinoin for increased minoxidil conversion
The conversation is about using Tretinoin with Minoxidil for hair loss treatment, discussing the effectiveness and personal experiences with different concentrations. The image linked in the post received negative reactions for being unpleasant.
community RU58841 for 10 months- no results. Anyone else?
RU58841 not working for hair loss after 10 months. Concerns about purity of experimental drugs.
community 8 months apart on the mother of all stacks
User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.