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      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 1 year ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 1 year ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

      community What happened to L'Oreal Serioxyl?

      in Treatment  6 upvotes 2 years ago
      A user noticing changes in the L'Oreal Serioxyl hair treatment, including a different smell, mismatched batch numbers, and a color change. They question if it's a new formula and seek alternatives to stemoxydine. Another user questions if the positive results were due to stemoxydine or other medications.

      community Anyone here who stopped microneedling and maintained or lost the gains?

      in Microneedling  9 upvotes 1 year ago
      Microneedling's long-term effects on hair loss are uncertain, with concerns about scarring and the need for continued use of minoxidil and finasteride to maintain gains. Finasteride does not sustain minoxidil-regrown hair without ongoing minoxidil use, and microneedling alone shows limited evidence of effectiveness.

      community why hair restoration has not been progressed for last 20 years?

      in Chat  32 upvotes 2 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.

      community Dutasteride mesotherapy - no result 4.5 months

      in Is this regrowth?  1 upvotes 3 months ago
      The user experienced significant hair thinning and has been using minoxidil, dutasteride mesotherapy, and red light therapy for 4.5 months without results. Suggestions include switching to oral dutasteride or finasteride for better effectiveness.

      community i'm Considering adding hair stimulant: stemoxydine or alphatradiol

      in Treatment  5 upvotes 1 year ago
      The user is considering adding Stemoxydine to their hair loss regimen, as they already use topical finasteride with rosemary and cannot use Minoxidil. They are seeking feedback on Stemoxydine and Alphatradiol, and another user mentions 2-deoxy-d-ribose as a potential option.

      community Is treatment working or should i switch?

      in General  99 upvotes 1 year ago
      The user started using topical finasteride 0.025% and minoxidil 5% for hair loss but is experiencing increased shedding after two months without signs of regrowth. They are seeking advice on when to expect results or consider switching treatments.

      community Am discouraged, tried just about everything....

      in Chat  4 upvotes 1 year ago
      The user has tried finasteride, minoxidil, dutasteride, microneedling, retinol, topical finasteride, and ketoconazole for hair loss but continues to experience hair recession. They are considering adding oral minoxidil or RU58841 and are unsure about the next steps.

      community lost all my gains switching from liquid to foam

       5 upvotes 7 years ago
      Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.

      community Dermaneedling+minox+tretinoin+azaleic acid and hair loss

      in Minoxidil  1 upvotes 6 months ago
      The user stopped oral treatments due to side effects and switched to a regimen of topical minoxidil, tretinoin, azelaic acid, and dermaneedling, with recent addition of topical finasteride. They are questioning the long-term effectiveness of non-hormonal methods and considering hair transplantation.

      community Notice any progress?

      in Question  5 upvotes 7 years ago
      A 23-year-old is using finasteride, minoxidil, nizoral, a dermapen, rosemary oil, and peppermint oil for hair loss treatment. They are seeking feedback on their progress.

      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  44 upvotes 4 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  291 upvotes 5 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Just got some test results back.

      in Finasteride/Dutasteride  5 upvotes 6 years ago
      The user received hormone test results showing normal estradiol and testosterone levels, low SHBG, and normal free androgen index. They are considering starting finasteride but are concerned due to being slightly overweight.

      community 23M Wierd blood test results after 7 months on finasteroid (1mg daily)

      in Finasteride/Dutasteride  5 upvotes 6 months ago
      A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

      community Oral Min shed is brutal . Do I keep going?

      in Minoxidil  94 upvotes 1 year ago
      The conversation discusses the experience of hair shedding after starting sublingual oral Minoxidil, with the user questioning whether to continue the treatment. Responses suggest persisting with the treatment as shedding might lead to positive results.

      community Just saw a post from a hyper responder to topical minoxidil and wanted to show my experience.

      in Progress Pictures  4 upvotes 3 months ago
      A user shared their 1-year and 3-month hair loss treatment progress using 0.5mg Dutasteride daily, topical and then oral Minoxidil, and microneedling, noting hair darkening and some side effects like watery semen and testicular pain. Despite initial setbacks after switching to oral Minoxidil, they are seeing progress and plan to increase the dosage.