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      community How nuts did your hairloss make you?

      in Question  8 upvotes 8 years ago
      Hair loss can cause significant stress and anxiety, leading individuals to try various treatments like microneedling, hair transplants, and lifestyle changes. Some people find peace by accepting hair loss and focusing on other aspects of life, while others experience ongoing distress.

      community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

      in Chat  17 upvotes 3 years ago
      The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

      community Anyone hear of Ursolic Acid?

      in Question  3 upvotes 6 years ago
      Ursolic acid, found in apple peels, lemongrass, rosemary, and lavender, may have anti-androgen effects similar to finasteride. It might be beneficial for hair health when used with other treatments like Minoxidil, Finasteride, and RU58841.

      community I waited long enough. Shedding since September. Starting RU58841

      in Treatment  11 upvotes 1 month ago
      The user experienced significant hair shedding after long-term use of finasteride and dutasteride and is now considering trying RU58841 as a last resort. They have checked health factors and suspect stress and poor sleep may contribute to the shedding, but they are determined to try RU58841 to see if it helps with androgenetic alopecia.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 weeks ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Could l-arginine be making hairloss worse?

      in Question  4 upvotes 7 years ago
      L-arginine may worsen hair loss by potentially increasing testosterone levels, especially in those with a DHT-sensitive gene. Users discuss the effects of increased nitric oxide on hair loss and consider stopping supplements like zinc and l-arginine to see if hair conditions improve.

      community My current stack/personal program

      in Update  1 upvotes 1 year ago
      The user is using RU58841, Revivogen, Regenepure ketoconazole shampoo, and plans to use a stimufield cap to address hair loss. They aim to avoid finasteride and minoxidil while hoping to stop hair loss and regrow hair.

      community Experiences with RU58841? Any results?

      in Research/Science  3 upvotes 8 months ago
      RU58841 is discussed for hair loss treatment, with mixed reviews on its effectiveness and side effects. Users mention using it in an ethanol/PG solution and combining it with other treatments like dutasteride.

      community RT1640 - Gray Hair Reversal Recipe

      in Research/Science  3 upvotes 3 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

      community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

      in Progress Pictures  31 upvotes 2 years ago
      A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community 3 year update - Dut, Min, Niz. 1.5mm roller

      in Progress Pictures  640 upvotes 8 months ago
      The user shared a 3-year hair restoration update using 0.5mg dutasteride daily, 5% minoxidil foam twice daily, a 1.5mm derma roller twice a month, and Nizoral shampoo. They reported significant improvement and maintenance of hair, with minimal side effects, and are satisfied with the results at age 40.
      Receding hairline / temples - asking for advice

      community Receding hairline / temples - asking for advice

      in General  114 upvotes 4 months ago
      The user is experiencing hair loss and has been using RU58841 but is considering pyrilutamide and minoxidil, avoiding finasteride due to side effects. Another user suggests finasteride or dutasteride as essential, possibly in topical form, while dismissing saw palmetto as ineffective.

      community I ingested RU58841 orally to see if its legit

      in Chat  133 upvotes 11 months ago
      A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

      in Is this regrowth?  86 upvotes 2 months ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

      community Overwhelming amount of anti-androgens

      in Female 3 years ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

      community Anyone know cheapest/best way to source RU58841 for Aussies?

      in Product  2 upvotes 1 month ago
      The conversation is about sourcing RU58841 for hair loss treatment in Australia and discusses the lack of effective alternatives. Alternatives mentioned include Kx826, fluridil, cb, alfatradiol, and topical spiro, but they are considered weak compared to RU58841.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 2 years ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Can I switch from Min to Nanoxidil?

      in Minoxidil  1 upvotes 1 year ago
      The user is considering switching from Minoxidil to Nanoxidil due to severe fatigue while continuing with Topical Finasteride and oral Dutasteride. They hope to maintain hair gains without the side effects of Minoxidil.