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      community RU58841 2.5% in Minoxidil 5% 3ml twice a day - Less Hairfall "BUT"

      in Treatment  2 upvotes 2 years ago
      The user mixed RU58841 with Minoxidil for hair loss treatment and experienced reduced hair fall and thicker hair but stopped due to chest pain and muscle twitching. They plan to use a new routine without RU58841 or Finasteride due to side effects, including various topical treatments and peptides.

      community There are no new treatments as of now.

      in Chat 3 years ago
      Treatments for androgenic hair loss, including the use of finasteride, minoxidil, nizroal and microneedling/dermarolling. Side effects are discussed and it is noted that while there are tradeoffs to taking medications, they are generally safe and effective.

      community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

      in Research/Science 1 year ago
      Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 1 year ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community 6 months on Pyrilutamide- no results

      in Treatment  20 upvotes 2 years ago
      A user applied pyrilutamide for 6 months without hair regrowth and is considering stopping due to cost and lack of results. Another user suggests switching to finasteride, which is cheaper and has shown regrowth for them.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  460 upvotes 9 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community RU58841 in germany eventually facing legal charges

      in Hair Systems  32 upvotes 1 year ago
      The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

      community Diffuse thinning chronicles pt. 2

      in Progress Pictures  16 upvotes 2 years ago
      A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 1 year ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community Homebrewing RU58841 as a gear user

      in Product  5 upvotes 3 months ago
      The conversation discusses using RU58841, Minoxidil, and finasteride for hair loss treatment. It focuses on homebrewing RU58841 while using other treatments.

      community pyrilutamide any results so far?

      in Treatment  44 upvotes 3 years ago
      The hair loss treatment Pyrilutamide and whether it has had any results for users. Martinsahara is planning to buy some soon.

      community Topical fin/minox + nizo shampoo and microneedling

      in Treatment  1 upvotes 3 months ago
      The user is using topical finasteride, minoxidil, nizoral shampoo, and microneedling for hair regrowth but hasn't seen results after 2-3 weeks. They added tretinoin to their routine and are advised to wait a few months for potential changes.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  102 upvotes 7 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community Wrap it up everyone. CB-03-01 is another failed treatment

      in Treatment  80 upvotes 9 months ago
      CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

      community Sulfate in Nizoral vs. Head & Shoulders

      in Ketoconazole 6 years ago
      The conversation discusses the presence of sulfates in Nizoral and Head & Shoulders shampoos. The user seeks advice on whether to return Head & Shoulders for a sulfate-free alternative and recommendations for a second shampoo/conditioner to alternate with Nizoral.

      community How much of a difference does catching it on time make?

      in Question  7 upvotes 8 years ago
      The user is experiencing early hair loss and is using finasteride, Rogaine, biotin, vitamin D3, and Nizoral. They are concerned about whether starting treatment early will help them keep their hair despite strong genetic predisposition to balding.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 9 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community any females on RU58841/minoxidil 2.5%?

      in Minoxidil  6 upvotes 4 years ago
      A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.

      community Anti Fibrosis and Calcification regimen?

      in Question  10 upvotes 8 years ago
      The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.

      community How bad is nicotine when it comes to hairloss

       10 upvotes 7 years ago
      The conversation discusses the impact of nicotine and caffeine on hair loss. The user has been using finasteride, minoxidil, and nizoral for hair loss treatment and is questioning whether to stop using nicotine products.

      community B5 (Pantothenic acid), B7 (Biotin), B12

      in Treatment  4 upvotes 2 years ago
      The conversation discusses the effects of B5 (Pantothenic acid), B7 (Biotin), and B12 on hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Experience with only Minoxidil and Nizoral

      in Minoxidil  6 upvotes 9 months ago
      Minoxidil and Nizoral alone are unlikely to stop hair loss effectively, as they do not address the root cause, which is often DHT. Many users suggest incorporating a 5AR inhibitor like finasteride or dutasteride for better results, despite concerns about potential side effects.

      community Can’t take fin - options/alts?

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.