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      community 4 month update - nuclear stack, 42m

      in Progress Pictures  256 upvotes 1 year ago
      A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

      community Finasteride vs RU58841 vs Dutasteride for MPB, Diffuse Thinning, or Retrograde Alopecia

      in Minoxidil  6 upvotes 1 year ago
      The user is seeking advice on the best treatment for male pattern baldness, diffuse thinning, and retrograde alopecia, comparing the effectiveness of finasteride, RU58841, and dutasteride, and considering whether to add minoxidil or switch to dutasteride or combine treatments. They are currently on finasteride and are contemplating if adding RU58841 or switching to dutasteride is better, and also asking about the comparison between pyrilutamide and RU58841.

      community 1 Month RU58841 + Minoxidil + Weekly microneedle

      in Minoxidil  1 upvotes 3 months ago
      The user is using RU58841, Minoxidil, and weekly microneedling for hair loss, having stopped finasteride due to side effects like low libido and depression. They are considering dutasteride as an alternative but are cautious due to past experiences with DHT blockers.

      community Is regrowth on an androgen receptor blocker possible?

      in Chat  11 upvotes 1 year ago
      RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.

      community Nuclear topical fin formulation?

      in Chat  1 upvotes 7 months ago
      The conversation discusses a hair loss treatment involving oral minoxidil, topical finasteride, and a custom topical formulation with minoxidil, cetirizine, finasteride, progesterone, and hydrocortisone. The user seeks advice on the effectiveness of these ingredients for diffuse thinning.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  20 upvotes 2 months ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

      community Painkillers May Block Minoxidil

      in Research/Science  15 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community Swapping from Fluridil to Pyrilutimide?

      in Treatment  1 upvotes 2 months ago
      The conversation discusses hair loss treatments, with the main focus on using Fluridil and considering switching to Pyrilutamide. Other treatments mentioned include minoxidil, topical finasteride, nizoral shampoo, and saw palmetto supplements, with advice to stick with Fluridil for at least six months before considering alternatives.

      community Has anyone had a hair transplant while on pyrilutamide?

      in Treatment  4 upvotes 1 year ago
      The user is considering starting pyrilutamide before a scheduled hair transplant, having previously used oral minoxidil and finasteride with worsening results. They also tried dutasteride, which worsened their hair and made their skin oily.

      community Pyrilutamide… After using it for four days.

      in Research/Science  36 upvotes 4 years ago
      User tried Pyrilutamide for hair loss and noticed less hair fall initially, but experienced more hair fall after four days. Others advised to assess results after a longer period and consider increasing dosage for better results.

      community Are Ru58841/Kx826 effective as fin?

      in Treatment  1 upvotes 1 year ago
      The user is considering switching from topical finasteride to RU58841 or KX826 due to side effects like low libido and ED. They are also using oral minoxidil and considering low-dose saw palmetto to maintain their hairline.

      community Pyrilutamide potential release date!

      in Update  9 upvotes 2 years ago
      The conversation discusses the potential release date of a hair loss treatment called Pyrilutamide. One user suggests it may be available in about 5 years.

      community Best solution for pyrilutamide in UK?

      in Treatment 2 years ago
      The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

      community My Pyrilutamide Experience so far

      in Update  78 upvotes 3 years ago
      A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

      community Is it a good idea to add RU58841 to finasteride? (No min)

      in Treatment  6 upvotes 5 months ago
      The user has been using finasteride for a year to stop hair loss and is considering adding RU58841 instead of minoxidil to further inhibit DHT. Another user suggests adding dutasteride for better DHT inhibition, but the original user cannot access it and is considering RU58841 despite potential side effects.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 5 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community important questions about RU58841

      in Research/Science  3 upvotes 2 years ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.