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      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community pyrilutamide solution progress log

      in Product  20 upvotes 3 years ago
      A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

      community 2-Deoxy-D-Ribose official Product

      in Research/Science  5 upvotes 1 year ago
      2-Deoxy-D-Ribose is discussed as a potential hair loss treatment, but skepticism exists due to lack of human testing. The original poster uses a combination of topical Minoxidil, oral Finasteride, topical RU58841, and other treatments, reporting some hair regrowth but not significant results.

      community Curious about 'nuclear' stacks

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

      community Alternative Approach to Hair Loss: an n=1 Experiment in Bioenergetics

       7 upvotes 6 years ago
      The post discusses a holistic, bioenergetic approach to hair loss, focusing on diet, exercise, and lifestyle changes rather than traditional treatments like finasteride or minoxidil. Key dietary recommendations include fruits, milk, potatoes, butter, coconut oil, eggs, oysters, liver, and gelatin, along with moderate exercise and lifestyle adjustments to reduce stress.

      community Genomic Sequencing for Hair Loss

      in Research/Science  156 upvotes 2 weeks ago
      Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community 10 Month Nuclear Stack Progress Update

      in Progress Pictures  151 upvotes 1 year ago
      The user experienced significant hair regrowth using a treatment regimen including finasteride, oral and topical minoxidil, RU58841, red light therapy, microneedling, and various supplements. They switched from dutasteride to finasteride due to side effects and reported improved results and well-being.

      community Update On Massages and Nutrient Intake at N2 Stabilization

      in Update  1 upvotes 7 months ago
      The user shared their experience with hair regrowth using a natural approach, including a good diet, multivitamins, pumpkin seed oil, and scalp massages, without using minoxidil or finasteride. They emphasize this method for those with stabilized hair loss around Norwood 1.5 - 2, noting satisfactory progress over a year.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 1 month ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community 2-deoxy-D-ribose (2dDR), a sugar molecule, was found to be 80%-90% as effective as minoxidil in promoting hair growth and neovascularization in androgenic alopecia models, showing promise for alopecia treatment.

      in Research/Science  19 upvotes 1 year ago
      2-deoxy-D-ribose, a sugar molecule, is found to be 80%-90% as effective as Minoxidil in promoting hair growth, showing potential for alopecia treatment. Concerns include high cost, lack of human studies, and possible side effects like diarrhea and nausea.

      community Anyone here has experience with ‘nuke’ protocols?

      in Research/Science  4 upvotes 4 years ago
      The conversation discusses aggressive hair loss treatments, including finasteride, dutasteride, minoxidil, topical cetirizine, and experimental options like Estrogel, oh-flutamide, and RU58841. Users share experiences and suggest trying oral minoxidil and el cranell, noting the complexity and challenges of treating hair loss.

      community Let Me Sell You on NAC

       15 upvotes 6 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community 3 Month Results with Nuclear Stack - 42M

      in Progress Pictures  114 upvotes 1 year ago
      A user shared 3-month hair regrowth results using a combination of oral Dutasteride, daily Minoxidil, RU58841, micro-needling, Keto shampoo, scalp massages, and supplements. Positive progress was noted, and encouragement to continue was given.

      community Shedding and thinning won’t stop on Nuclear protocol

      in Treatment  20 upvotes 2 years ago
      The user is using a combination of hair loss treatments including dutasteride, minoxidil, RU58841, low-level laser therapy, ketokonozole, supplements, Viviscal, Nutrafol, microneedling, PRP, and scalp Botox injections, but is still experiencing hair shedding and thinning. Despite being on this regimen for two years, the user's hair condition is worsening, and they are seeking advice on what else they can do.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2447 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Pyrilutamide cease and desist from Kintor

      in Transplants  12 upvotes 3 years ago
      Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Using the nuclear stack and still losing hair... Is this the end for my hair?

      in Update  4 upvotes 3 years ago
      The user is experiencing ongoing hair loss despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, cyproterone acetate, transdermal estradiol, and topical bicalutamide. They suspect cyproterone acetate may be worsening their hair loss and are considering switching to injection monotherapy.