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      community What do we currently know about clascoterone?

      in Chat  5 upvotes 5 months ago
      Clascoterone is seen as a promising topical treatment for hair loss, similar to finasteride but without side effects, though concerns exist about its long-term effectiveness. Other treatments discussed include topical minoxidil, ketoconazole, microneedling, and oral options like dutasteride and minoxidil.

      community Topical finasteride in liposomal formulation

      in Finasteride  5 upvotes 6 years ago
      Topical finasteride in a liposomal formulation reduces systemic absorption compared to ethanol solutions. The user is seeking sources for such products, noting that popular options like morr-f are not liposomal.

      community Hypertrichosis goals (yes, yes R2M)

      in General  115 upvotes 1 year ago
      The user aims to achieve a hypertrichosis look and has used topical Minoxidil for 20 years, now trying oral Minoxidil in a low dose. They seek alternatives to Minoxidil to avoid side effects.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Verteporfin to deminiaturize follicles

      in Research/Science  8 upvotes 3 years ago
      User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

      community RU58841 - Has anyone tried it before?

      in Research/Science  8 upvotes 1 month ago
      RU58841 is discussed as an effective hair loss treatment, with some users experiencing regrowth and reduced shedding, but concerns about safety and sourcing are raised. Users advise against purchasing from Amazon, recommending reputable sources and cautioning about potential side effects like cardiovascular issues.

      community Potential Cure?! Verteporfin- unlimited HT

      in Research/Science  42 upvotes 2 years ago
      The conversation discusses verteporfin as a potential treatment for hair regeneration, which could lead to unlimited hair transplants by healing the donor area. Some users are considering using verteporfin now, while others are hopeful it will be available for future hair transplants.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Redensyl Megathread !!!!

       42 upvotes 6 years ago
      Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

      community My experience with Alfatradiol so far

      in Treatment  10 upvotes 3 years ago
      User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

      community 30% min cream nightly, 5% min mornings, fin, 1.5 derma pen weekly, .5 micro needling daily for min absorption, Daily multivitamin w/ Biotin, LLT every other day,daily scalp massages, Hims shampoo and daily coffee rinse. Hoping for some reversal. I’ll post update in 1 yr 5/15/2023. Wish me luck

      in Product  12 upvotes 4 years ago
      The post and conversation are about a hair loss treatment regimen involving 30% minoxidil cream nightly, 5% minoxidil in the mornings, finasteride, weekly 1.5 derma pen, daily 0.5 microneedling for minoxidil absorption, daily multivitamin with biotin, low-level laser therapy every other day, daily scalp massages, Hims shampoo, and daily coffee rinses. The user hopes for hair regrowth and plans to update in one year.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Dermarolling for the next 4 months

      in Treatment  11 upvotes 7 years ago
      The user plans to dermaroll and use minoxidil for hair loss over the next 4 months, documenting progress monthly. They will also consider finasteride later and include vitamins, a custom shampoo, castor oil, scalp massages, and increased water intake in their regimen.

      community Alfatradiol and Fluridil enough? Thoughs on topical fin?

      in Treatment  4 upvotes 2 years ago
      The user is currently using alfatradiol and fluridil for hair loss and is considering adding low-dose topical finasteride but is concerned about potential side effects due to past mental health issues. They are seeking others' experiences with these treatments and their effectiveness.

      community Where to buy Latanaprost or equivalent?

      in Treatment  2 upvotes 8 months ago
      The conversation discusses using Latanoprost for hair regrowth, with the original poster seeking advice on where to purchase it without a prescription. Users suggest alternatives like Triple Hair's TH-07, which includes Finasteride, Minoxidil, and Latanoprost, and Strut's Latanoprost with melatonin and caffeine.

      community Retinol substitute for Tretinoin

      in Minoxidil  4 upvotes 1 year ago
      The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.

      community Has Anyone Gotten Results With TH16?

      in Product  5 upvotes 3 years ago
      The conversation discusses using TH16, a topical melatonin with resveratrol, and stemoxydine for hair maintenance, avoiding finasteride and minoxidil due to side effects. The user is considering a low-dose topical finasteride despite sensitivity.