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      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 3 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community Before Oral Minoxodil vs 3 months (2.5)

      in Is this regrowth?  15 upvotes 1 year ago
      The user is using 2.5mg oral minoxidil and Nizoral shampoo for hair regrowth, noticing some improvement. They are considering increasing the dosage and exploring alternatives to topical minoxidil/finasteride due to concerns about toxicity to cats.

      community 2 in 1 min and fin spray by him m26

      in Is this regrowth?  4 upvotes 10 months ago
      The user regrets not using medication after a failed hair transplant and is now using a combination of minoxidil, finasteride, derma rolling, oils, and ketoconazole shampoo to try to improve hair regrowth. They are seeking feedback on progress and considering further treatment options.

      community Using Maneup Instead of Minoxidil

      in Progress Pictures  103 upvotes 1 year ago
      A 51-year-old woman switched from Minoxidil to Maneup, a copper peptide treatment, experiencing initial hair loss but later regrowth with different hair texture. Users debated Maneup's effectiveness, with some considering it alongside finasteride.

      community 2 months on topical min and fin.

      in Progress Pictures  1 upvotes 1 year ago
      The user has been using topical Minoxidil (5%) and finasteride (0.1%) twice daily for 2 months, with occasional missed applications. They also use a zinc pyrithione shampoo every 2 days and do not dermaroll.

      community Thoughts on this 2-deoxy-D-ribose Topical?

      in Treatment  27 upvotes 1 year ago
      The post and conversation are about skepticism towards a new hair loss treatment containing 2-deoxy-D-ribose, copper peptides, and exosomes, with concerns about the legitimacy of the product and its website. The treatment's effectiveness and authenticity are questioned due to lack of testing and transparency.

      community The Hormonal Profile of MPB/AGA

      in Research/Science  9 upvotes 5 years ago
      Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 6 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community GT20029 Will Replace Finasteride For Hair Loss

      in Research/Science  50 upvotes 1 month ago
      GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Minoxidil experiment on single hair follicle

      in Minoxidil  1697 upvotes 1 year ago
      Minoxidil was applied to a single miniaturized hair follicle over four months, resulting in less miniaturization but not yet terminal growth. The user used a 5% minoxidil solution, specifically the Regaine brand, and observed changes using a handheld WiFi microscope.
      Eliminate/Confirm AGA based on blood report

      community Eliminate/Confirm AGA based on blood report

      in General  126 upvotes 11 months ago
      A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

      community Nuclear stack not working still

      in Progress Pictures  1 upvotes 5 months ago
      A 20-year-old has been using topical minoxidil since 2021, oral finasteride since 2023, oral minoxidil for 6 months, and dutasteride for 2 months to combat hair loss but is still experiencing temple thinning. Suggestions include continuing medication, considering a future hair transplant, and taking monthly progress pictures.

      community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?

      in Question  1 upvotes 9 years ago
      Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  33 upvotes 3 months ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community Prediction: Scube3 is never coming out

      in Research/Science  6 upvotes 2 years ago
      Scube3, a potential hair loss treatment, is unlikely to be released because it was given to a startup company, Amplifica, which may go bankrupt and fail to bring the treatment to market. Amplifica is prioritizing other treatments over Scube3, which could lead to financial loss and the end of Scube3's development.