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      community Riken develops new method for culturing hair follicles

       41 upvotes 8 years ago
      A new stem cell method for culturing hair follicles is being developed as an alternative to Minoxidil, finasteride, and RU58841. There are concerns about its cost and accessibility despite plans for commercialization.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community M22 with 2 years of treatment min/fin/microneedle/ketoconazole

      in Is this regrowth?  10 upvotes 2 months ago
      A 22-year-old male has been using oral minoxidil, oral finasteride, microneedling, and ketoconazole for hair loss treatment over two years, experiencing some regrowth and maintenance. He reports side effects from finasteride, including erectile dysfunction, and slight libido impact from minoxidil.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 10 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Extreme hair and beard growth from Stemoxydine. Big 3 + 1?

      in Product  23 upvotes 5 years ago
      Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.

      community Someone here experience with/or knows stories of cancer-patience regrowing hair?

      in Chat  20 upvotes 5 years ago
      Hair regrowth after chemotherapy varies; some experience thinner or differently colored hair, while others may see fuller regrowth. Treatments like essential oils, vitamins, and lifestyle changes are discussed, but no specific medications like Minoxidil or Finasteride were used by the original poster.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  7 upvotes 1 year ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Methionine? Glycine?

       6 upvotes 10 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Need some advice for my mom any help would be appreciated

      in Female  7 upvotes 3 years ago
      User seeks advice for mom's hair loss, considering treatments like spiro, iron/biotin supplements, 2% minoxidil, and Nioxin. Mom has Parkinson's and low estrogen due to hysterectomy, which may contribute to thinning.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community Combining Stemoxydine + Topical Minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Combining stemoxydine with topical minoxidil for hair loss treatment. Users discuss application order and effectiveness, with some skepticism about stemoxydine's benefits.

      community I don’t know what to do at this point

      in Female  87 upvotes 1 year ago
      A 21-year-old woman with female pattern baldness has tried minoxidil, red light therapy, and supplements without success. She is considering spironolactone and seeking medical advice.

      community MicroRNA can regrow 90% of lost hair, researchers find

      in Treatment  502 upvotes 3 years ago
      Researchers finding that microRNA can potentially regrow 90% of lost hair, and the challenges involved in moving this research forward to human trials. Various treatments for hair loss, such as finasteride and minoxidil, have been discussed.

      community Haircafe video on Min Sulfate, thoughts?

      in Research/Science  101 upvotes 7 months ago
      Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.

      community PP405 Phase 2a press release with early results

      in Research/Science  700 upvotes 1 year ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Which mesotherapy should I choose?

      in Research/Science  1 upvotes 2 years ago
      A user is considering adding PRP and mesotherapy to their hair loss treatment and is deciding between two options: Promoitalia, which contains Phosphatidic acid, Riboflavin, and Superoxide dismutase, and the more expensive Melsmon, a human placenta derivative. They seek advice on which option to choose based on effectiveness and scientific backing.

      community This Stuff Consumes Us Young People With No Mercy

      in Update  43 upvotes 5 months ago
      A young person struggling with hair loss switched from finasteride to 0.5mg dutasteride and Oral Minoxidil 2.5mg, hoping for improvement before graduation. They are considering a hair transplant and exploring other treatments like stemoxydine and hair fibers, while dealing with the emotional impact of early balding.

      community Extremely potent catalyst for Minoxidil

      in Minoxidil  5 upvotes 6 years ago
      Using Megatek with minoxidil significantly increases hair growth, especially vellus hairs, but is less effective alone. Biotin and ketoconazole shampoo are also used to support hair health.