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      community 1 year and 10 months progress on oral fin + topical min

      in Progress Pictures  124 upvotes 1 year ago
      A 33-year-old male shares his successful hair regrowth journey using oral finasteride (1.25 mg daily) for 22 months and topical minoxidil for 10 years, along with dermarolling. He reports significant hair regrowth, no side effects, and emphasizes the importance of consistency in his routine.

      community I am Transitioning to Oral Minoxidil after 3 years

      in Treatment  13 upvotes 9 months ago
      The conversation is about transitioning from topical to oral Minoxidil for hair loss treatment, with additional use of Finasteride and Dutasteride. The user reports no side effects from oral Minoxidil and hopes for better results despite experiencing shedding during treatment changes.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 1 year ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

      community I fought the reaper, and won!!

      in Progress Pictures  1024 upvotes 10 months ago
      A user shared their successful hair regrowth journey using oral minoxidil, dutasteride, and eucapil, with additional benefits from MTF hormone replacement therapy. They advised consulting specialists and considering individual responses to treatments.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 3 years ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Norwood Reaper got the Iron Man himself

      in Shaved/buzzed  34 upvotes 3 years ago
      The conversation is about Robert Downey Jr. shaving his head, likely for a movie role, and comments on his appearance and strong genes. No specific hair loss treatments like Minoxidil, finasteride, or RU58841 are mentioned.

      community 2 months of Oral .5 Fin 2.5 Min - Let me know your thoughts!

      in Is this regrowth?  160 upvotes 1 year ago
      The user is experiencing positive hair regrowth after two months of using oral finasteride (0.5 mg) and minoxidil (2.5 mg) and is considering a hair transplant. They are seeking advice on surgeons closer to the U.S. and discussing potential side effects and alternative treatments.

      community VDPHL01 phase-2/3 results comparison

      in Research/Science  120 upvotes 2 days ago
      The conversation discusses hair loss treatments, focusing on a new slow-release oral minoxidil compared to topical minoxidil and finasteride. The results show that twice-daily dosing of the new treatment is slightly more effective than once-daily, but concerns about cost, side effects, and the accuracy of reported results remain.

      community Anagenic is trying to compound Gt20029

      in Treatment  54 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community 1 Year after TE. Scarred scalp

      in Progress Pictures  8 upvotes 8 months ago
      Hair loss after telogen effluvium (TE) with thinning and possible scarring, treated with 5 mg oral minoxidil. Concerns about scarring alopecia and lack of regrowth, with suggestions to consider finasteride for better results.

      community 21m, curious about what's going on with my hair

       6 upvotes 11 years ago
      A 21-year-old male with a thyroid condition noticed his hair thinning uniformly without a receding hairline. He is considering using a 5ARI to prevent further baldness if he starts TRT.

      community PP405 Phase 2a press release with early results

      in Research/Science  694 upvotes 10 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  737 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  132 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 4 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Results from oral treatment vs topical

      in Finasteride/Dutasteride  4 upvotes 11 months ago
      The conversation discusses switching from oral to topical treatments for hair loss, specifically using a mix of retinoic acid, finasteride, and minoxidil, after oral treatments like dutasteride and finasteride were ineffective. The user is concerned about the cost and potential impact of dandruff on the absorption of topical treatments.

      community Oral Minoxidil Changes to Vellus Hair

      in Is this regrowth?  2 upvotes 1 year ago
      A person in their early 30s has been using finasteride for about 10 years and recently started oral minoxidil, vitamin chewables, and dermarolling to address hair loss. They noticed pigmented vellus hairs and potential regrowth, questioning if oral minoxidil is more effective than topical due to enzyme differences.