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210-240 / 1000+ resultscommunity Have there been any recent Amplifica updates?
Hair loss discussion includes Amplifica, a new treatment by Dr. Rassman and Dr. Plikus using molecules from hairy moles. No progress updates mentioned.
community Starting Spironolactone, any ladies in here with experience or success?
A female user starting Spironolactone treatment for thinning hair, and others sharing their experiences with Minoxidil and oral/sublingual Minoxidil as treatments.
community I asked Gemini 2.5 Pro to roast r/tressless
Hair loss concerns and treatments like Minoxidil and Finasteride are humorously discussed. The community's quirks and dedication to battling hair loss are highlighted.
community Should I just keep trusting my medicine?
A user noticed hair thinning and was prescribed spironolactone, which led to increased hair loss. They were advised to switch to finasteride.
community Instagram ad with a ridiculously bold claim. What are the chances that it is even remotely true?
The conversation is about skepticism towards a hair serum advertised on Instagram, with users doubting its effectiveness and one sharing a personal negative experience with the product.
community TWIST-1 and the cure: Is it really that easy?
TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
community Since there is so much hype for cosmeRNA and HMI-115...
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
community Are there any news about scube3? Did they want to start the clinical trials soon?
The conversation is about skepticism regarding new hair loss treatments until they are FDA approved. People have been joking about treatments being 5-7 years away for decades.
community I guess i’ll stop asking AI about hair questions
The conversation humorously discusses hair loss and subtle differences in hairlines, with references to Norwood scale stages. It satirizes the idea of asking AI for hair advice.
community Other factors involved then DHT/5aR
community Opinions & Experiences with topical Spironolactone?
Hair loss discussion includes topical Spironolactone's effectiveness and minimal side effects. Community members share personal experiences and opinions on its use.
community CB-03-01 / Breezula Personal Results
The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.
community I was in pub toilet cubicle and overhead a guy speaking to himself in mirror about his hair
Man talks about hair loss in pub toilet. Users discuss avoiding mirrors and group therapy for hair loss.
community Got a microscope camera. Here’s the difference between healthy and miniaturized hair
A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.
community Any interesting future treatments around the corner
community Has anyone tried this method? I have never heard of this before.
community Why are people so negative regarding Clascoterone (Breezula)?
Clascoterone (Breezula) shows promising hair growth results, but skepticism remains due to past disappointments with new treatments. It may be a good alternative for those who can't tolerate finasteride or dutasteride, and can potentially be combined with them and minoxidil for better results.
community What hair loss pattern is this?
The user noticed small circular hairless spots after a buzz cut and has been using finasteride, dutasteride, and oral minoxidil for hair loss. They are experiencing continuous shedding and thinning, and it is suggested they consult a dermatologist for a scalp examination and possible biopsy to determine if it's alopecia areata or androgenetic alopecia.
community At what dose did Spironolactone really start working?
A user is asking women with androgenic alopecia about the effective dose of spironolactone for hair regrowth, mentioning they've been on 100 mg for a year with minimal results and considering increasing the dose. The conversation focuses on the effectiveness of spironolactone for hair loss treatment.
community Modifiability of the aging process
community And just like that, everyone stopped talking about Clascoterone?
Clascoterone showed promising initial results for hair regrowth but failed to replicate them, leading to disappointment. Users discuss combining it with minoxidil and other treatments, noting its current availability only in lower concentrations.
community Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles
miR-205, a tiny RNA, can stimulate hair growth by softening aging hair follicle stem cells in mice. Future tests aim to see if this can work in humans.
community Topical spironolactone question
User started using topical spironolactone on scalp and face, experienced fever feeling and sluggishness. Asks if side effects are normal or systemic.
community 8 months of hair / scalp regrowth
community Anyone hear about Stemson's presentation at the 2021 Global Hair Loss Summit?
community Is the combination of spironolactone and estrogen more or less effective than finasteride?
community UCLA scientists found a molecule — PP405 — that wakes up sleeping hair follicles and tells them, “Do your job.”
PP405 is a promising molecule that may reactivate dormant hair follicles, potentially offering a new treatment for hair loss. It is in phase 2 trials, with possible availability between 2027 and 2030.
community 5mg oral minoxidil + 100mg Spironolactone
A user shared progress pictures using 5mg oral minoxidil and 100mg spironolactone, noting increased body hair and faster nail growth. Another user humorously suggested a new sub for people with similar experiences.
community Regrowth or miniaturization? 2 months on min And spironolactone
The conversation is about hair regrowth or miniaturization after two months of using minoxidil and spironolactone. Specific treatments mentioned are minoxidil and spironolactone.