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GlossaryOsteoarthritis

chronic joint condition causing cartilage breakdown and pain

Osteoarthritis (OA), also known as Degenerative Joint Disease, is a chronic condition characterized by the breakdown of cartilage in the joints, leading to pain, stiffness, and reduced mobility. It commonly affects weight-bearing joints such as the knees, hips, and spine, and is often associated with aging, repetitive stress, or joint injury.

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community Scalp inflammation cleared after stopping "spoiled" milk - what about follicles,shedding?

in Treatment 2 upvotes 1 month ago

Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as hair cycles progress.

community Derm stopped me from using Minoxidal

in Update 55 upvotes 5 months ago

A dermatologist advised stopping minoxidil due to heavy shedding, suggesting alternative treatments like Betaval Lotion and supplements, but many users disagreed, recommending continuing minoxidil and adding finasteride for better results. The conversation highlights skepticism about the dermatologist's motives and emphasizes the importance of understanding the type of hair loss before choosing treatments.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 49 upvotes 1 year ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community How uninformed the general public is about hair loss

in Chat 319 upvotes 2 years ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community An arthritis drug that can be used for Alopecia.

in Research/Science 4 upvotes 4 years ago

An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.

community Scarring Alopecia and NSAIDs?

in Female 3 upvotes 5 years ago

The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

community can someone help me identify these pls

in Treatment 4 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 1 year ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 2 weeks ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

community Can gains from stemoxydine be permanently kept with 5AR inhibitors?

in Research/Science 1 year ago

Stemoxydine's effects on hair growth are uncertain and not well-studied, with users reporting mixed results and concerns about maintaining gains. Some users combine it with 5AR inhibitors like Dutasteride, but results vary, and conditions like lichen planopilaris complicate treatment.

community PCOS female with significant receding and thinning; doctor won’t give me anything but Spiro and Spiro sucks

in Female 5 upvotes 3 years ago

Female with PCOS experiences receding and thinning hair, wants dutasteride instead of spironolactone. Discusses desire to reduce DHT without losing libido.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

in Research/Science 10 upvotes 5 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community Hair Loss Worsened After Switching From Arimidex to Raloxifene, Despite Dutasteride

in General 178 upvotes 7 months ago

Switching from Arimidex to Raloxifene worsened hair loss despite using Dutasteride. The user added oral Minoxidil, dermastamping, and RU58841 to their regimen to address the issue.

community Olumiant alternative for Alopecia Areata?

in Treatment 1 upvotes 3 years ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community Fin/dut increase in estrogen and autoimmune diseases

in Chat 6 upvotes 3 years ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

23 upvotes 8 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

community Low dose spiro with 5ARI inhibitor

in Chat 2 upvotes 1 year ago

Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.

community grass fed collagen worked for my alopecia

in Female 11 upvotes 6 years ago

A woman found that taking grass-fed collagen powder helped with her alopecia, leading to hair regrowth and reduced hair loss. She initially took it for gut issues, not hair, and also noticed improvements in arthritis and reduced bruising.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

in Research/Science 247 upvotes 2 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Fluridil degrades the androgen receptor.

in Research/Science 12 upvotes 10 months ago

Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Depressed that DUPA rules me out of a transplant

in Chat 7 upvotes 2 years ago

A user is upset about hair loss due to seborrheic dermatitis and DUPA, which prevents a hair transplant. They mention using jojoba oil and discuss treatments like Minoxidil, finasteride, and RU58841.

community 19M: Finasteride Causing Gyno? Considering Anastrozole for Hair Loss Treatment

in Finasteride 143 upvotes 1 month ago

A user is experiencing side effects from topical finasteride and is considering using a low dose of anastrozole to manage potential gynecomastia while continuing finasteride for hair loss. They are unsure whether to start the aromatase inhibitor immediately or wait to see if their body adjusts.

community Autoimmune disease and balding

in Update 12 upvotes 1 year ago

A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

community What are the alternatives to spironolactone for AGA?

in Female 8 upvotes 1 year ago

The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

community Attempting to assist people who experience gyno on finasteride

in Finasteride 352 upvotes 1 year ago

Finasteride can cause gynecomastia due to hormonal imbalances, and using an aromatase inhibitor like anastrozole can help manage these side effects. It's important to work with an endocrinologist to address these issues safely.

community will long term 5ar inhibition alter my physical appearance?

in Treatment 2 upvotes 1 year ago

A 19-year-old concerned about long-term effects of 5AR inhibitors on physical appearance. They have used finasteride and plan to try dutasteride or RU58841; responses suggest improved skin, hair, and confidence.

community Spiro for AGA in Europe

7 upvotes 6 years ago

Treatment options for female alopecia androgenetica, discussing the availability of spironolactone online in The Netherlands and other potential treatments like finasteride, minoxidil and RU58841.

community Does age play a role in how you respond to 5AR inhibitors? (finasteride/dutasteride)

in Research/Science 24 upvotes 2 years ago

The conversation discusses whether age affects the side effects and effectiveness of hair loss treatments like finasteride and dutasteride. Some believe early treatment yields better results, while others mention varied outcomes across ages and personal regrowth experiences without a clear consensus on age impact.

community update (late 20s woman, ongoing worsening hairloss): put on spironolactone

in Female 15 upvotes 4 years ago

Late 20s woman struggles with worsening hair loss and tried various treatments without success. Now trying spironolactone and ketokonazole shampoo, hoping for improvement.