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      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  13 upvotes 4 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 5 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community Buzzing it to gauge results, thoughts?

      in General  136 upvotes 1 year ago
      The user is considering buzzing their long hair to better assess the effects of finasteride, which they have been using for over two months, and is concerned about maintaining their unique appearance. They are also curious if dyeing short hair could cause any issues.

      community 7.5 month closeup hairline comparison

      in Is this regrowth?  7 upvotes 1 year ago
      The conversation is about hair regrowth progress using topical finasteride and minoxidil twice daily, with occasional microneedling. The user also uses Minoxidilmax and WOW Skin Science Apple Cider Vinegar Shampoo.

      community 10 Month Hairline Update from Fin+Min

      in Progress Pictures  122 upvotes 10 months ago
      The user shared a 10-month hairline update using 5% topical Minoxidil and 2.5% oral Finasteride, noting some improvement despite a second shedding phase. They switched to oral Minoxidil for convenience, which may have caused the shedding.

      community Can't do Fin...Do DHT shampoos actually work?

      in Finasteride  3 upvotes 7 years ago
      A user stopped using finasteride due to reduced efficacy and health concerns, and is considering minoxidil and DHT-blocking shampoos for hair loss. Another user responded that DHT-blocking shampoos are ineffective.

      community Pattern hair loss could be due to gut bacteria

       51 upvotes 6 years ago
      Feeding bacteria-free mice with Lactobacillus murinus worsened hair loss, but a regular diet with biotin stopped it. The conversation suggests gut bacteria and diet may influence hair loss, with some skepticism and discussion about other factors like DHT and genetics.

      community Anyone looking at peptides for hair?

      in Treatment  10 upvotes 2 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community Hair loss research is a money grab

      in Chat  227 upvotes 5 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community STEM CELL TREATMENT FOR HAIR LOSS at home

      in Treatment  6 upvotes 5 years ago
      User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

      community Realistic timeline for hair regeneration and follicle cloning?

      in Technology  6 upvotes 1 month ago
      Hair regeneration and follicle cloning are considered far from being feasible, with current treatments like finasteride, minoxidil, and hair transplants expected to remain dominant for the next 15-20 years. Some are hopeful that AI advancements might accelerate progress, but many remain skeptical about significant breakthroughs in the near future.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 2 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community I don’t get it - I keep shedding hair even 2 years into fin

      in Chat  15 upvotes 1 year ago
      OP is experiencing ongoing hair shedding despite two years on finasteride, with some initial improvement but no long-term success. Users suggest seasonal shedding, checking for vitamin deficiencies, considering minoxidil, and possibly switching to dutasteride.

      community The case for 5ARI-free hair transplants: Dr. Zarev, Pittella, Sethi, Miln, and future treatments in development

      in Treatment  12 upvotes 5 months ago
      Some individuals experience side effects from 5AR inhibitors like finasteride and are considering hair transplants without these medications, with some opting for surgeons like Dr. Zarev. Others are exploring alternative treatments and waiting for new medications in development, while some discuss managing side effects through lifestyle changes or additional medications.

      community Why is human evolution like this 😂

      in Chat 3 years ago
      Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

      community It's over. Hairline has fallen. Millions must shave.

      in Update  467 upvotes 2 years ago
      The conclusion of the conversation is that the user has tried various medications and treatments for hair loss, including minoxidil, finasteride, microneedling, and nizoral shampoo, but has not seen any progress. They have decided to shave their head. Other users suggest options such as hair transplants, RU58841, hair units, and scalp micropigmentation.

      community "DHT Itch" and onset Seborrheic Dermatitis

      in Research/Science  76 upvotes 2 years ago
      The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

      community My challenging hair transplant surgery update

      in Progress Pictures  407 upvotes 8 months ago
      A user shared their positive experience with a hair transplant surgery, detailing the process and results, including the use of 2800 grafts and post-surgery treatments like PRP. They also mentioned using finasteride, minoxidil, and supplements to maintain hair growth.

      community 12 Months Hair Transplant Progress / 3500 Grafts (1 YEAR)

      in Transplants  1117 upvotes 1 year ago
      A user shared their 12-month progress after a 3500-graft hair transplant at Heva Clinic in Istanbul, choosing not to use minoxidil or finasteride. The results were praised, with comments noting the natural look and significant improvement.

      community Hair routine (all info listed)

      in Treatment  4 upvotes 3 years ago
      The user shares a hair loss routine involving finasteride, B-Complex vitamins with biotin, pumpkin seed oil, apple cider vinegar, aloe vera, honey water, olive oil, and tea tree oil. They emphasize avoiding shampoo and using natural rinses to maintain scalp health and promote hair growth.