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The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

The user initially had success with Minoxidil for hair loss but stopped due to life changes, resulting in hair loss returning. They plan to restart treatment with Minoxidil, add Nizoral, dermarolling, and supplements like saw palmetto and beta-sitosterol, while avoiding pharmaceutical drugs.

A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

A 30-year-old shared their successful hair restoration journey using a combination of liposomal topical finasteride and minoxidil, vitamins, and a second hair transplant in Greece, resulting in life-changing improvements without side effects. The user emphasized the importance of proper research for hair transplant clinics and expressed gratitude for finding an effective treatment protocol.

Topical finasteride in the UK is sought after due to concerns about the strength and cost of Hims products. There is also interest in whether crushing finasteride pills into minoxidil is effective.

A user shared their positive experience with a clinical trial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.

The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

Switching from topical to oral minoxidil may cause initial hair shedding, but oral minoxidil is likely more effective. Shedding should be temporary, and results should be monitored over a few months.

KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.

A user had two hair transplant surgeries, using a total of 6850 grafts from the scalp, beard, and chest, costing around $20,000 USD, and is happy with the results, though the crown may not be as dense as the hairline. They experienced no scarring from the donor areas and noted that transplanted beard and chest hair are thicker and curlier.

A user reported worsening hair shedding and thinning after 6 months of daily dutasteride, despite also using minoxidil, bicalutamide, and recently adding RU58841. They are considering stopping dutasteride due to lack of improvement.

A user visited a dermatologist for hair loss and was prescribed Minoxidil without a physical examination, leading to skepticism about the thoroughness of the appointment. The user is considering seeking a second opinion due to the lack of tests or physical checks.

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

A user is considering using verteporfin with microneedling, oral/topical minoxidil, and RU58841 to treat hair loss. They seek advice on dosage and application methods.

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Update on HMI-115 clinical trial expected in July or August.

Finasteride's impact on fertility is discussed, with users sharing experiences of conceiving while on the medication. Concerns about long-term safety are also mentioned.

The user is undergoing Mesotherapy and Low-Level Laser Therapy for hair loss, with plans for multiple sessions. They are also using oral finasteride, topical minoxidil, dutasteride, and hair fibers.

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.

Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.

User shared 1-year progress after hair transplant and regimen including topical finasteride, minoxidil, viviscal, biotin, and sulfate-free shampoo/nizoral. Users praised results and discussed application frequency and side effects.

A person shared their positive experience with a hair transplant at Sule Hair Transplant in Istanbul, performed by Dr. Selahattin Tulunay using the Hybrid FUE technique with 5,000 grafts, costing €2,990. The user reported significant hair growth and satisfaction at 3, 6, and 12 months post-surgery, without using finasteride or minoxidil, but faced skepticism from others about the authenticity of their post.

The user experienced hair regrowth using a combination of Minoxidil, Finasteride, and RU58841, with Minoxidil used initially and the other treatments added later. The user believes the combination of Finasteride and RU58841 contributed to the regrowth, with RU sourced from MVsupplement.

User shared 15-month results using finasteride and minoxidil, showing no loss but minimal growth, considering a hair transplant. Replies suggest starting treatment earlier, continuing current treatment, or getting a transplant.

User is experiencing severe hair loss despite using finasteride for 15 months, losing 500 hairs a day and 50% density since June. Minoxidil with needling was ineffective, and RU58841 is too expensive and hard to obtain.

The user, SnooDonuts9235, shares their positive experience with a hair transplant and using topical finasteride and minoxidil. They express concern about increased shedding and ask if it is normal. Other users compliment their results and ask about the clinic and procedure details. SnooDonuts9235 encourages others to consider a hair transplant even without taking oral finasteride and shares that the procedure was not as scary as they initially thought.

A 28-year-old man had a hair transplant in India, choosing not to start finasteride due to past side effects with other medications but will use minoxidil for six months post-surgery. He researched and selected a clinic in Mumbai with a high reputation, underwent a 9-hour procedure for $965, and is optimistic about the results.

The user has tried various hair loss treatments including minoxidil, finasteride, and others, experiencing side effects and is seeking recommendations for a knowledgeable doctor in the California Bay Area. They had a negative experience with one doctor and are considering a hair transplant but want to avoid further side effects.

The user shared their hair regrowth journey since 2017, using treatments like finasteride, minoxidil, dutasteride, RU58841, microneedling, and later feminizing HRT. Significant progress was noted after starting HRT, with continued improvement in hair texture and regrowth.