community Pyrilutamide Update Number Two
How Pyrilutamide, a hair loss treatment, has improved texture and regrowth of hair without any side effects for users, who are encouraged to post progress photos.
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810-840 / 1000+ resultscommunity Spironolactone and pregnancy planning
A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.
community ISO a topical without minoxidil
A user seeks a topical hair loss treatment without minoxidil, considering options like finasteride, dutasteride, caffeine, tretinoin, or prostaglandin analogues. Recommendations include products like Strut, Maximus, Zeuss, and custom formulas from compounding pharmacies.
community Low topical fin + 0.5% pyrilutamide
Using a combination of low-dose topical finasteride (0.025%) and 0.5% pyrilutamide for hair loss, with a focus on minimizing side effects. The user seeks experiences and results from others who have tried this combination.
community Progreso de 3 meses usando minoxidil topico
The user started using topical minoxidil 5% and ketoconazole shampoo for hair loss, noticing minimal progress after three months, with fine hairs appearing. They experienced a setback when reducing the application to once a day but resumed twice daily applications.
community Possible explaination for Finasteride Reflex Hyperandrogenicity
The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.
community B6,Zinc and acid azelaic inhibit 90% of scalpe DHT according to this study how to make the same topical formulation
The conversation is about creating a topical hair loss treatment with B6, zinc, and azelaic acid, which is claimed to inhibit 90% of scalp DHT. One user is skeptical about the effectiveness of this treatment and its comparison to other treatments without side effects.
community Stabilized hairloss without sides (finally)
User found hair loss stabilization without side effects using a topical solution of 0.008% Finasteride, 2% RU, and Stemoxydine. Other treatments like Eucapil, Fluridil, RU-monotherapy, and Pyrilutamide didn't work for them.
community I have heard that Amplifica - Scube3 initiate a human study for AGA, but I cannot find any information about it from clinictrial.gov. Amplifica did not state it is a phase 1 clinic trial or not, it says it is "The initiation of our first-in-human clinical study"
The conversation is about a user seeking information on a clinical trial by Amplifica - Scube3 for Androgenetic Alopecia (AGA). The user is unsure if it's a formal phase 1 study.
community Should I stick to minox + RU58841, add Pyrilutamide or just switch to only minox + pyrilutamide?
A 26-year-old is considering switching from a regimen of minoxidil, finasteride, and RU58841 to possibly include pyrilutamide due to insufficient results in slowing hair loss. They are seeking advice on whether to add pyrilutamide or replace RU58841 with it, considering cost and effectiveness.
community Started fin .25mg ED on 9/19/25
The user started taking 0.25mg finasteride daily on 9/19/25, along with using 2% ketoconazole, rosemary oil, and dermastamping. They are hesitant to add minoxidil due to heart palpitations.
community What do you think about this topical formula?
The conversation discusses a topical formula for hair loss including Finasteride (0.025%), Minoxidil (0.5%), Tretinoin (0.01%), Caffeine (0.005%), Melatonin (0.003%), Tea Tree Oil (0.05%), Aloe (0.05%), Biotin (0.05%), and Fagron TrichoXidil (2.5%). The user considers removing Minoxidil and Tretinoin to test TrichoXidil's effectiveness.
community Minoxidil without coconut derivatives? (coconut allergy) (glycerin, cetyl alcohol)
A user is seeking a Minoxidil solution without coconut derivatives due to a coconut allergy and is considering DIY options from pure Minoxidil tablets. They mention that Rogaine contains glycerin and cetyl alcohol, which are derived from coconut.
community Winlevi for 1 month on scalp. Testing it out so y’all don’t have to.
A user is testing clascoterone (Winlevi) on their scalp for hair loss and has noticed a reduction in scalp sebum after one month. They are also using other unspecified treatments and plan to provide an update after the second month.
community Any early Kintor's KX-826 experiences?
The conversation is about experiences with Kintor's KX-826 for hair loss, specifically regarding side effects. Some users reported side effects from grey market versions, questioning their authenticity.
community Mixing topical minoxidil and alfatradiol
Mixing minoxidil and alfatradiol in one bottle may affect their effectiveness due to potential stability issues. It's recommended to apply them separately for full benefits.
community My Pyrilutamide Experience Update 2 Part 2 PICS
The user's experience with Pyrilutamide for hair loss treatment, including their belief that it has sparked improvements in combination with other treatments such as Minoxidil and Finasteride. Another user was also hoping to see results from using Pyrilutamide alone.
community 8 months - 2,5mg OM / Topical MinFin
User shares 8-month hair growth progress using 2.5mg oral minoxidil and 2ml topical minoxidil/finasteride mix. Others comment on noticeable improvement and discuss user's journey and treatment details.
community Alfatradiol and bad side effects
Using alfatradiol can cause nausea and headaches. Users discuss these side effects and seek advice.
community Who said GT20029 would be applied only few times per month?
The conversation discusses the safety and effectiveness of a hair loss drug, GT20029, and the possibility of infrequent application, with users hoping for once-daily use and speculating on the drug's duration of effect on the scalp. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
community Topical caffeine is a common ingredient in formulas to prevent hair loss and to induce hair regrowth. (What’s your take on this?)
The conversation discusses whether topical caffeine is effective for hair loss, with some users questioning its role due to its vasoconstrictive and vasodilative properties, while another suggests that temporary vasoconstriction might be beneficial by promoting angiogenesis. Specific treatments mentioned include caffeine shampoo, which one user believes is ineffective.
community Side effects of topical azelaic acid?
Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.
community Does Apple cider vinegar interfere with oral minoxidil or finasteride?
Apple cider vinegar, when taken as 1 tablespoon diluted with water daily, does not interfere with the absorption of oral minoxidil or finasteride.
community is there a pyrilutamide group/discord to discuss results?
Discussing results, side effects and potential sources of pyrilutamide for hair loss treatment alongside RU58841 and other treatments such as Minoxidil and finasteride.
community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?
Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.
community Topical melatonin/cetirizine instructions
User shares a topical hair loss solution using melatonin and cetirizine to help reduce shedding and itching. Instructions provided for creating and using the mixture, with additional lifestyle tips for overall hair health.
community Chest pain on Oral minoxidil (18M)
An 18-year-old experienced chest pain, headaches, and vomiting after taking oral minoxidil for hair loss. They reduced the dosage, felt better, but experienced sharp chest pain again after increasing it, and are advised to stop the medication and see a doctor.
community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?
The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.
community Very exited about Veradermics,
Veradermics is a promising new treatment for hair loss, essentially a repackaged version of Minoxidil. The user is optimistic about its potential effectiveness.
community Dry and itchy scalp after ru58841 and keto. Advice needed
The user experienced severe scalp itching after using RU58841 and ketoconazole shampoo, despite trying moisturizing treatments. They suspect the issue is related to the propylene glycol in the vehicle and are seeking alternatives.