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      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 11 months ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community Anyone heard of Nanoxidil??

      in Treatment  4 upvotes 5 years ago
      Nanoxidil, a minoxidil derivative, is being discussed as a potential hair loss treatment. Users are curious about its effectiveness and side effects compared to minoxidil, with some noting it includes additional ingredients like caffeine.

      community Best minoxidil formulation for best results?

      in Minoxidil  2 upvotes 1 year ago
      The conversation discusses creating a customized minoxidil formulation with tretinoin, azelaic acid, and caffeine, but there are concerns about foam stabilization due to acidity. The user seeks advice on the best formulation for effective results.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 3 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Seriously confused about minoxidil's method of action

      in Minoxidil  6 upvotes 3 years ago
      The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

      community Help labing up hair preservations

      in Research/Science 1 year ago
      The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  11 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Topical 5% minoxidil vs compounded topical spray

      in Minoxidil  3 upvotes 1 week ago
      A user is considering switching from regular 5% minoxidil foam to a compounded 5% minoxidil spray with added caffeine, melatonin, and tretinoin for easier application and potentially better results. Another user mentions that tretinoin can enhance minoxidil's effectiveness by converting it to its active form.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 8 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community New molecule PP405 vs exercise

      in Research/Science  40 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Question for RU users and regular usage

      in Finasteride/Dutasteride  4 upvotes 3 years ago
      The user is experiencing increased hair shedding while using finasteride and RU58841, possibly due to changes in application methods. They are considering adding minoxidil and stemoxydine to their regimen to improve results and manage hair greasiness.

      community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?

      in Question  1 upvotes 9 years ago
      Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.

      community Feel like im not making process. Had insane shed. (Min/Fin/HRT)

      in Progress Pictures  3 upvotes 5 days ago
      The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.

      community Retinol from the ordinary for minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Retinol or tretinoin may improve minoxidil absorption and effectiveness. The user is considering using The Ordinary's 1% retinol as tretinoin is hard to get in their country.

      community Alternatives to 5% Foam minoxidil causing redness and itchy scalp

      in Treatment  1 upvotes 1 year ago
      The user experienced redness and itching from using 5% minoxidil and is considering trying a lower dose or alternative treatments like 2% minoxidil, mesotherapy, PRP, or rosemary oil. They are seeking advice on managing side effects and exploring other options for hair stimulation.

      community Oral min 2.5mg closing in on 3 months

      in Progress Pictures  372 upvotes 3 years ago
      _the_orange_box_'s experience using oral minoxidil, with discussion about finasteride and the potential side effects of both treatments. Other users shared their own experiences related to hair loss treatments.

      community How to mix ru58841 powder into minox??

      in Treatment  2 upvotes 1 year ago
      Mixing RU58841 powder into minoxidil can result in undissolved particles. Shaking the bottle and breaking up the grains may help dissolve it better.

      community Oral Min Aging reversible?……..

      in Minoxidil 6 months ago
      Oral minoxidil may cause temporary facial puffiness, leading to a perception of accelerated aging, but it doesn't cause actual aging. Concerns about hair loss and treatments like minoxidil and finasteride are discussed, with suggestions to use tretinoin and sunscreen to mitigate potential side effects.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 1 year ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community 10 months progression (plz respond)

      in Is this regrowth?  4 upvotes 2 weeks ago
      The user is experiencing hair shedding after using minoxidil and is considering switching to dutasteride while planning to increase their oral minoxidil dose. They also use nicotine pouches, Vyvanse, and GHK-Cu, and have noticed thicker eyebrows and lashes from oral minoxidil.

      community ORAL MIN ,DERMAROLLING AND RU58841 PROGRESS 3 months (18,M)

      in Progress Pictures  80 upvotes 3 years ago
      The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.