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      community oral hyaluronic acid supplements?

      in Treatment  4 upvotes 4 years ago
      Oral hyaluronic acid is not beneficial for hair, as it gets broken down in the stomach and has no strong evidence supporting its effectiveness. The user is taking finasteride, dutasteride, and topical minoxidil for hair loss, but combining finasteride and dutasteride is considered redundant.

      community RU58841 5% is roughly equivalent to Dutasteride 2mg — here's why

      in Research/Science  37 upvotes 1 month ago
      RU58841 5% is theoretically equivalent to 2mg of dutasteride for hair loss treatment, with RU58841 offering higher potential but more variability due to absorption issues. Users discuss the effectiveness of RU58841 and dutasteride, with some preferring dutasteride for consistent results and others finding success with RU58841.

      community Losing ground on dut for 1.5y daily

      in Finasteride/Dutasteride  6 upvotes 8 months ago
      The user has been using 0.5mg Dutasteride daily and topical Minoxidil but is experiencing worsening hair density and is considering switching to Finasteride, increasing the Dutasteride dose, or adding RU58841. They are also considering microneedling and have concerns about the effectiveness of generic Dutasteride compared to branded versions.

      community Clascoterone 5% solution infographic

      in Update  130 upvotes 4 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community Latanoprost from the gray market?

      in Chat  4 upvotes 1 year ago
      The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community Experience with CB (Breezula)?

      in Research/Science  4 upvotes 5 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community 8 months of 0.5 mg dut daily, 14 months of 5 mg oral min

      in Progress Pictures  3 upvotes 1 week ago
      The user has been using 0.5 mg dutasteride daily for 8 months and 5 mg oral minoxidil for 14 months to address hair thinning. Despite some users seeing no change or improvement, the user feels their hairline density has decreased and corners have worsened.

      community Any active Kx-826 Pyrilutamide group buys happening?

      in Product  10 upvotes 4 years ago
      The conversation discusses organizing group buys and tracking progress for Kx-826 Pyrilutamide, a hair loss treatment. Participants express optimism about upcoming results and concerns about self-reporting bias.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 2 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community 36yo male, NW6, 2.5mth dut/minox

      in Progress Pictures  1 upvotes 1 year ago
      A 36-year-old male using dutasteride and minoxidil has seen significant hair regrowth, confirmed by a dermatologist and supported by before-and-after photos. He plans to increase his oral minoxidil dosage and add dermapen to his routine.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  185 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

      in Treatment  14 upvotes 4 years ago
      The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.

      community Any other non-responders to most medications?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  4 upvotes 5 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Fluridil does work if used as add-on treatment.

      in Treatment  6 upvotes 2 years ago
      The user has been using Dutasteride for five years and noticed slow thinning on the frontal hairline. They tried Fluridil as an additional treatment, which resulted in noticeable hairline thickening after two months.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  172 upvotes 4 months ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.