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      community New molecule PP405 vs exercise

      in Research/Science  37 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Stemoxydin and hair cycle question

      in Treatment  2 upvotes 2 years ago
      The user has been using Finasteride for hair loss and is considering adding alphatradiol, stemoxydine, or 2% minoxidil to their regimen. They are concerned that stemoxydine, which shortens the resting phase of hair, might accelerate hair loss in those not using Finasteride by depleting hair cycles without strengthening miniaturized hairs.

      community 20M on dut for 2 months a long with 5mg monoxdil

      in Is this regrowth?  20 upvotes 6 months ago
      A 20-year-old is using minoxidil and dutasteride for hair regrowth and is questioning if recent changes are due to regrowth or lighting. Users suggest the changes are due to minoxidil and advise not to worry about hair shedding from dutasteride.

      community Stemoxydine- lifelong use? curious.

      in Treatment  4 upvotes 2 years ago
      The conversation discusses whether stemoxydine needs to be used for life for hair loss treatment. One user suggests that stemoxydine does not require lifelong use and can make hair exit the resting phase faster, but the benefits may be temporary.

      community 1.25mg oral minoxidil effectiveness

      in Minoxidil  6 upvotes 2 days ago
      The conversation discusses the effectiveness and side effects of taking 1.25mg oral minoxidil for hair loss, with some users suggesting starting at a lower dose to minimize side effects before potentially increasing to 2.5mg. Concerns about cardiovascular side effects and the importance of individual responses to dosage are highlighted.

      community This true? Sult1a1 enzyme booster 2025

      in Technology  8 upvotes 1 year ago
      The conversation discusses the potential effectiveness of a Sult1a1 enzyme booster in enhancing the results of minoxidil for hair loss. Users express interest in the booster, hoping it will improve the effectiveness of oral minoxidil, especially for those who struggle with topical application.

      community Retinol from the ordinary for minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Retinol or tretinoin may improve minoxidil absorption and effectiveness. The user is considering using The Ordinary's 1% retinol as tretinoin is hard to get in their country.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 7 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Temple revival. Dropping Oral min.

      in Chat  5 upvotes 9 months ago
      The user experienced negative side effects from oral minoxidil, including cardiac issues and excessive sweating, and decided to switch to topical minoxidil while using other treatments like RU58841, Setipiprant, Azelaic acid, and latanoprost. Another user suggested splitting the oral minoxidil dose to reduce side effects.

      community Rosemary Oil experiment 4 months in

      in Research/Science  46 upvotes 5 days ago
      A user experimented with applying pure rosemary oil to a single hair strand twice daily, observing increased thickness and pigmentation, but questioned if the oil or the application method caused the change. Some users noted rosemary oil might be as effective as 2% minoxidil for hair growth, though others warned about potential harm from using undiluted oil.

      community Progress at 4 month mark dut/min

      in Progress Pictures  10 upvotes 4 months ago
      A 24-year-old is using 1 mg oral dutasteride and 1 mg oral minoxidil daily, along with monthly mesotherapy including zinc, dutasteride, minoxidil, biotin, and panthenol, to treat hair loss. The user is considering increasing the minoxidil dose but will consult with their doctor first.

      community 4 months of daily minoxidil usage

      in Progress Pictures  8 upvotes 9 months ago
      The user shared progress after 4 months of using topical minoxidil daily, along with dermastamping and Nizoral shampoo. They are seeking suggestions for better results.

      community I just made 60x of 5mg minoxidil sugar cubes

      in Minoxidil  1337 upvotes 1 year ago
      A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

      community Iron Overload and Vitamin D Deficiency - Male Hair Loss

      in Treatment  17 upvotes 4 years ago
      The conversation discusses hair loss treatments, specifically minoxidil, vitamin D supplements, and the potential impact of iron overload. The user experienced hair regrowth with high-dose vitamin D but faced hair thinning again after reducing the dosage, and is now exploring the role of iron overload in hair loss.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Question for all the good Minoxidil responders

      in Minoxidil  8 upvotes 1 year ago
      The user discusses their experience with minoxidil for hair loss, noting that drinking coffee may reduce its effectiveness. They observed better results with the liquid solution and no coffee compared to using the foam solution and drinking coffee.

      community i'm Considering adding hair stimulant: stemoxydine or alphatradiol

      in Treatment  5 upvotes 1 year ago
      The user is considering adding Stemoxydine to their hair loss regimen, as they already use topical finasteride with rosemary and cannot use Minoxidil. They are seeking feedback on Stemoxydine and Alphatradiol, and another user mentions 2-deoxy-d-ribose as a potential option.

      community 2.5 months of oral minoxidil 5mg

      in Progress Pictures 3 years ago
      This conversation is about a user's progress with using oral minoxidil 5mg to treat their hair loss, in combination with finasteride. The replies discuss the effectiveness of this treatment and provide additional information on potential methods for obtaining it.

      community Seen Alfatradiol mentioned on here a few times recently and found this study - in case anybody is interested. Translated from German.

      in Treatment  5 upvotes 4 years ago
      Alfatradiol (0.025%) is an effective and safe treatment for androgenetic alopecia in both men and women, increasing anagen hair rates with minimal side effects. Users discuss its cost-effectiveness and ease of use compared to other treatments like finasteride and RU58841, with some combining it with stemoxydine and Minoxidil.

      community Starting 5mg oral min after being on 2.5mg since February

      in Update  3 upvotes 4 months ago
      The user is increasing their oral minoxidil dosage from 2.5mg to 5mg after using 1mg finasteride and topical minoxidil foam for over three years without desired results. They have also been microneedling and using tretinoin cream, recently increasing the tretinoin dosage to 0.1%.

      community Growth stimulants worth a damn besides minox?

      in Minoxidil  3 upvotes 2 years ago
      The user experiences side effects from minoxidil and is considering alternatives like stemoxydine and adenosine for hair regrowth and density, but finds options like caffeine and various oils unreliable. They are also using a 5AR inhibitor (finasteride).