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      community Pyrilutamide / KX-826 / Koshine — has it been working for you?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide/KX-826 is being discussed for its effectiveness in hair regrowth, with some users reporting positive results, especially in early hair loss cases. Users have combined it with treatments like Minoxidil, and some experienced initial shedding before seeing regrowth.

      community What’s the view on stemoxydine?

      in Product  5 upvotes 11 months ago
      Stemoxydine may work synergistically with minoxidil and finasteride for hair growth, but its effectiveness is debated, with some users experiencing minimal results and concerns about cost. Users suggest sticking to proven treatments like minoxidil and finasteride, while considering stemoxydine as an additional option.

      community Thoughts on Pantostin Alfatradiol?

      in Treatment  10 upvotes 4 years ago
      User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

      community Almost 11-Months of 1.25mg Fin EOD | 23M

      in Progress Pictures  53 upvotes 8 months ago
      A 23-year-old male shared his 11-month progress using 1.25mg finasteride every other day and Nizoral/Dermazole, reporting reduced hair fall and new hair growth without major shedding. Users discussed the risks of finasteride for younger individuals and suggested consulting a doctor, with some recommending minoxidil as an alternative.

      community Pyrilutamide with Alfatradiol and minoxidil (23M)

      in Treatment  2 upvotes 6 months ago
      The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

      community Oral min vs topical comparison

      in Treatment  10 upvotes 1 year ago
      Oral minoxidil is claimed to be more effective and easier to use than topical minoxidil, with a 100% response rate, but it may cause unwanted body hair growth and has potential heart-related side effects. Topical minoxidil is less effective for many due to enzyme limitations, can cause scalp issues, and is more challenging to apply, but it avoids systemic side effects.

      community Vinpocetine and topical Minoxidil

      in Minoxidil 2 years ago
      A 25-year-old is using vinpocetine to enhance the absorption of topical Minoxidil for hair loss. They also use a hair tonic and supplement with Glycine, Taurine, Creatine, and Citrulline.

      community Creating an all-in one topical. Dumb idea?

      in Treatment 3 years ago
      The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.

      community Pyrilutamide 4 Month Journey with progress Pics..!!!

      in Progress Pictures  21 upvotes 10 months ago
      The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

      community Ordered copper peptides - how to apply?

      in Treatment  1 upvotes 1 year ago
      Gizzela is unsure about the dosage and frequency of copper peptides and asks if they can be used with Stemoxydine. They seek advice on applying these treatments together.

      community Does anyone have any experience with Stemoxydine?

      in Product  10 upvotes 3 years ago
      Using Stemoxydine, a hair growth promoter, in conjunction with Fin and Minoxidil to help counter shedding induced by the latter two treatments. Another user also shared their experience of using Stemoxydine for three months along with dermastamp.

      community Pyrilutamide almost for 9 months

      in Progress Pictures  62 upvotes 2 years ago
      The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 1 year fin/min topical .3/6% results once a day

      in Progress Pictures  6 upvotes 7 months ago
      The user shared progress pictures after using a topical treatment of 0.3% finasteride and 6% minoxidil once a day for a year, noting improvement in the front but needing suggestions for the crown. They confirmed using a product from Hims.

      community 7 months of min 2x a day + .25mg fin 1x a day

      in Progress Pictures  509 upvotes 1 year ago
      User shared progress pictures after 7 months of using 0.25mg finasteride daily and 1ml minoxidil twice daily, reporting no side effects and being thrilled with the results. Other users discussed the effectiveness of lower doses and the psychological impact of potential side effects.

      community DIY Minoxidil mix with Fin, Caffeine, Cetirizine, and Melatonin?

      in Treatment  4 upvotes 11 months ago
      A user plans to create a custom topical solution by adding finasteride, caffeine, cetirizine, and melatonin to a minoxidil bottle, questioning the stability and effectiveness of this mix. Concerns include potential crystallization and solution muddiness with added ingredients.

      community Eucapill and less shedding

      in Treatment  7 upvotes 5 years ago
      Eucapill 2% used for 1 month reduced shedding from 200 to 10/20 hairs daily with no side effects. Finasteride caused side effects like ED and watery semen.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community 12 Months 1mg Oral Fin 5mg Min

      in Progress Pictures  394 upvotes 8 months ago
      A 24-year-old user shared their 12-month progress using 1mg oral finasteride and 5mg oral minoxidil for hair loss, reporting significant improvement after initially starting with 2.5mg minoxidil. They experienced no side effects and noted thicker eyelashes, with results becoming noticeable around the 9th or 10th month.