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community PP405 timeframe ? Could it replace current treatments ?

in Update 34 upvotes 11 months ago

PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

community Molecular mechanisms triggered by Micronedlling -- Intersting Publication to better understand Dermarolling

24 upvotes 7 years ago

This post and conversation are about the molecular mechanisms triggered by microneedling, specifically its effects on inflammation, tissue remodeling, epithelial proliferation, differentiation, and collagen synthesis. The discussion highlights the potential benefits of microneedling for hair loss treatment.

community cb-03-01 research chem (winlevi/clascoterone cream)

in Technology 3 upvotes 2 years ago

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

community Kintor’s GT20029 Phase 1 success

in Update 74 upvotes 3 years ago

Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

community guys can we consume NMN(Nicotinamide mononucleotide) while being on dutasteride?

in Chat 1 upvotes 1 year ago

NMN is considered safe to use with dutasteride, and it may help reduce grey hairs. Combining NMN with creatine, whey protein, fish oil, and dutasteride is not seen as excessive.

community Breezula or kx-826 which one is better ?

in Technology 3 upvotes 10 months ago

Breezula (cb-03-01) and kx-826 are discussed as hair loss treatments. Kx-826 is available on Kintor's website, while Breezula is available on the grey market.

community 30, Dut, Min, Keto - now + needling + RU/Min/Fin/Dut topical

in Progress Pictures 28 upvotes 3 years ago

Hair loss treatment progress with Dut, Min, Keto, needling, and RU/Min/Fin/Dut topical. User noticed improvement, believes RU and needling most effective.

community Nicotinamide Riboside Experience

in Research/Science 4 upvotes 4 years ago

Nicotinamide Riboside (NR) significantly reduced hair loss for the user. They found science.bio's NR to be effective, unlike other brands.

community Why doesn't phase 3 of PP405 start straight away?

in Chat 14 upvotes 6 months ago

Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

community PP405 Phase 2a press release with early results

in Research/Science 700 upvotes 1 year ago

PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

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