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600-630 / 1000+ resultscommunity RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)
The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.
community PYRILUTAMIDE VS RU58841 users which is superior
Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.
community Pyrilutamide and RU alternatives?
Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.
community Solution vehicle used by compounding pharmacy
The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.
community 2 week difference W/ micro needle, RU58841, oral minox 2.5, topical minox, ketoconazole shampoo, and dutasteride.
The conversation is about hair regrowth using micro-needling, RU58841, oral and topical minoxidil, ketoconazole shampoo, and dutasteride. Users suggest that noticeable results take longer than two weeks, though one user mentions seeing baby hairs.
community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)
A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.
community What is this? what should be the treatment for it? my dermatologist tried selling prp and stuff? should i have gone with that?
The user is using oral minoxidil for hair loss and is considering its effects on facial hair. They are advised that minoxidil can help with facial hair, but a DHT blocker like finasteride is needed for head hair.
community Fin EOD, topical min 1x day, keto 2x a week, Vitamin D3 + Zinq - Some progress, i hope for more. Temples gotton better too, lots of babyhairs everywhere.
The user reports progress in hair regrowth using finasteride every other day, topical minoxidil once daily, ketoconazole twice a week, and Vitamin D3 with zinc. They note improvement in temple areas and the appearance of baby hairs.
community October 2025 $120M funding round for PP405 — hype justified or too early to celebrate?
Pelage secured $120 million for PP405, a non-hormonal topical hair loss treatment, sparking debate on its potential as a breakthrough. Concerns about finasteride's side effects persist, with some suggesting alternatives like topical finasteride or dutasteride.
community Topical Dutasteride (Switching from Oral) Proven results
Switching from oral to topical dutasteride may reduce side effects like anxiety and depression while maintaining hair health. Combining it with minoxidil, Nizoral, and dermarolling could be effective for hair preservation.
community Almost 3 months on pyrilutamide
A user's experience with Pyrilutamide, which they have been taking for 3 months to treat their aggressive male pattern baldness. The user reported that the medication decreased shedding and was hopeful it would work as advertised.
community Anyone in Pyrilutamide currently?
User considers trying Pyrilutamide for hair loss and itch relief. Another user shares positive experience with Pyrilutamide, no side effects.
community Breezula Phase 3 Results enough for maintenance?
Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.
community 1 years update [Finasteride, 5 mg oral minoxidil and recently topical minoxidil with 1.5 mm dermarolling]
Making a 1 year update on hair loss treatment of Finasteride, 5 mg oral minoxidil and topical minoxidil with 1.5 mm dermarolling; the user experienced some face pimples, baggy eyes, and had tried skin care. They also used fiber with their hair product and left it for a few days to make it look visually better. Replies were positive and one asked if using both oral and topical minoxidil was overkill.
community 23M, switched topical solution and experiencing increased shedding
A 23-year-old male switched to a topical solution containing Fin 0.1% and Min 5% from a previous solution with Fin 1% and Min 5%, noticing increased hair shedding. He is concerned about losing around 50 hairs while using ketoconazole shampoo.
community Requesting Experiences: Topical Dutasteride - Liposomes vs. DMSO vs. Trichosol Results?
The conversation discusses experiences with topical dutasteride for hair loss, comparing formulations from FUEClinic, MinoxidilMax, and Strut. Users share their results and side effects, with some preferring topical over oral treatments to minimize systemic absorption.
community Does anyone know what % of DHT does topical azelaic acid blocks?
The conversation is about the effectiveness of topical azelaic acid in blocking DHT for hair loss treatment. Specific treatments discussed include Minoxidil, finasteride, and RU58841.
community Pyrilutamide six month update photos
A six month update of the users' experience with Pyrilutamide, a hair loss treatment that combines Minoxidil, Finasteride and RU58841.
community Is RU58841 or pyrilutamide a stronger topical anti-androgen?
The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.
community 26/F - Lots of stuff going on - Pics inside.
A 26 year old female with PCOS who has been dealing with hair loss for several years, despite managing her hormones and taking vitamins. She has tried various treatments such as Nizoral, Minoxidil, Pyrithione zinc, coal tar and salicylic acid to no avail. The user is looking for advice on what else they can do to stop their hair loss.
community Pyrilutamide 6 months another result pictures
A user's six month progress with Pyrilutamide, a hair loss treatment; they experienced positive results such as stopped itching and shedding, as well as regrowth, without any side effects.
community Scalp Sunburns cause permanent hair loss. UPF hats protect you. Watch if you use Tretinoin on the scalp
Sunburns on the scalp can cause permanent hair loss, especially for those using Tretinoin or Tacrolimus. Wearing UPF 50+ hats is recommended to protect against UV radiation.
community pyrilutamide – did anybody had any success on it?
Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.
community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community 4 months of topical min, fin, keto, dermastamp, rosemary and peppermint oil
The conversation discusses a person's 4-month hair loss treatment regimen using topical minoxidil, finasteride, ketoconazole, a dermastamp, and rosemary and peppermint oils. Progress pictures are shared to show the results.
community Tiny tiny hairs outlining juvenile hairline
The conversation is about hair regrowth using high-dose dutasteride, oral minoxidil, and microneedling. Users discuss seeing tiny hairs and hope they will become terminal, with advice to use derma rolling weekly for better results.
community Adding dut with fin to stop dht itch
A user is seeking advice on adding dutasteride to their finasteride regimen to stop DHT-related scalp itch. They have tried selenium sulfide and ketoconazole shampoos with temporary success.
community 1 month progress. Fin+minox+dermarolling+ketoconazole
After one month of treatment with finasteride, minoxidil, dermarolling, ketoconazole shampoo, hair vitamins, and vitamin D3, the user reports minimal visual progress and increased shedding, but notes stronger body hair and light fuzz on eyebrows. The user is inquiring about potential hair regrowth.
community 4.5 Months on oral dut 0.5mg, oral min 5mg, topical RU 80mg, weekly microneedling at 1.5mm
User tried oral dut 0.5mg, oral min 5mg, topical RU 80mg, and weekly microneedling at 1.5mm for hair loss. Others commented on the significant improvement and potential for future hair transplant.