community My next option should be what? After a transplant.
The user is unsatisfied with their hair transplant and is considering another transplant, PRP, exosomes, or stem cells. They currently use topical minoxidil, dutasteride, and tretinoin.
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840-870 / 1000+ resultscommunity Topical caffeine is a common ingredient in formulas to prevent hair loss and to induce hair regrowth. (What’s your take on this?)
The conversation discusses whether topical caffeine is effective for hair loss, with some users questioning its role due to its vasoconstrictive and vasodilative properties, while another suggests that temporary vasoconstriction might be beneficial by promoting angiogenesis. Specific treatments mentioned include caffeine shampoo, which one user believes is ineffective.
community Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity
Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.
community Dutasteride mesotherapy could practically cure the world of balding.
Dutasteride mesotherapy showed increased hair density and diameter without reducing serum DHT levels in a small study. However, the sample size was too small to make definitive claims about its efficacy.
community anybody actually got botox on their scalp and had success?
The user is considering Botox for scalp hair loss and currently uses finasteride, minoxidil, microneedling, pumpkin seed oil, saw palmetto, and green tea extract. They seek information on potential risks and effectiveness.
community Are there any affects of using hair fibers while micro needling
The conversation discusses concerns about using hair fibers while microneedling, specifically the potential for clogging pores. It is suggested that microneedling should not cause bleeding.
community Any concrete cases of people who were told they couldn't have a transplant because of microneedling?
Microneedling before a hair transplant may harden the scalp and affect blood circulation, potentially impacting graft growth. Some users report successful transplants after microneedling, while others advise caution and consulting with a surgeon.
community Anyone else have one chad hair? This thing has somehow held on for dear life for years and years, like an inch past my hairline. Should donate this mf’s follicle to science
Hair loss discussion with a focus on a single resilient hair, jokingly called "chad hair," that remains despite hairline receding. Some users suggest microneedling and hair follicle cloning as potential treatments.
community A reasonably reputable guy claims that he has reversed his hairloss. Could be an interesting read.
A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.
community What vehicle is being used in the breezula trial?
The conversation is about identifying the vehicle used in the Breezula (clascoterone) trial for hair loss. No specific treatments were mentioned.
community Should I apply my grapefruit topically instead of injecting it into my bloodstream?
The conversation is a satirical discussion about using grapefruit for hair regrowth, with suggestions ranging from injecting it to applying it topically or anally. Some users claim unusual benefits like emitting a green aura or jumping high.
community Microneedling is the key ? Pics after 3 months
The user added microneedling to their routine of minoxidil and finasteride, resulting in noticeable hair regrowth after three months. They shared photos showing significant improvement.
community Wrap it up everyone. CB-03-01 is another failed treatment
CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.
community Scientists have finally found the potential ‘cure’ for baldness
A new study that found a single chemical could potentially be responsible for hair loss, and the potential to use this discovery to stimulate hair growth. The conversation also includes various treatments such as Minoxidil, Finasteride, RU58841, microneedling, DUT, and Botox for hair loss.
community Topical VPA - Anyone experiences here?
The conversation is about using topical valproic acid (VPA) for hair loss, focusing on its application method, usage frequency, and combination with other treatments like micro-needling. No specific experiences with VPA were shared.
community Will Pp405 be the Ozempic of bald Guys
PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.
community You want growth but don't use a Dermaroller
Using a dermaroller can enhance hair regrowth, especially when combined with minoxidil, and is recommended at depths of 0.75-1.5mm weekly. Microneedling boosts absorption and blood flow, and red light therapy is also being considered for hair growth.
community Been Microneedling for 4 weeks. Positive results, however, quite slow.
The user has been microneedling for 4 weeks and using treatments like minoxidil and eclipta alba oil, seeing positive but slow results. They are considering peppermint oil as a potentially more effective alternative to minoxidil.
community Regrowing my hair in just 7 weeks. No drugs, just massage and natural oils with microneedling and Keratin shampoo
The conversation is about a person regrowing their hair in 7 weeks using scalp massages, peppermint oil, microneedling, and keratin shampoo without drugs. They experienced initial shedding but saw improvement after consistent treatment and shampooing every other day.
community 1.5 years on dutasteride and on and off microneedling
The user experienced hair regrowth using dutasteride daily, microneedling weekly, and Nizoral shampoo, after stopping minoxidil due to side effects. They also use a mix of pumpkin seed, rosemary, and peppermint oil, and are considering RU58841 for more temple area thickness.
community How effective is microneedling without minoxidil?
Microneedling alone may not be effective for hair regrowth, though it can improve skin and reduce scars. Minoxidil caused heart palpitations for one user, leading them to stop its use.
community Minxodil collegen synthesis decrease?
Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.
community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?
Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.
community How many non responders to minoxidil become responders with 1.5mm microneedling?
The conversation discusses using 1.5mm microneedling to improve responses to Minoxidil for hair loss. One user humorously suggests more aggressive microneedling.
community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."
Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.
community Microneedling Isn’t Snake Oil — It’s Evidence-Based. Let’s Talk Studies, Not Fear.
Microneedling is supported by research as an effective adjuvant treatment for hair loss, especially when combined with Minoxidil or Finasteride, with minimal side effects if done properly. Concerns about long-term safety and potential risks like infection or fibrosis remain, but many users report positive results.
community This could be it!!! New treatment increase hair 500%
Clascoterone (Breezula) shows a potential 500% increase in hair growth, possibly outperforming minoxidil and finasteride. It is in advanced trials, with hopes for FDA approval, but cost and side effects are concerns.
community Binding affinity of pyrilutamide!
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
community Stemson Therapeutics and hair cloning pipeline
The conversation discusses the progress and potential of hair cloning by Stemson Therapeutics, questioning if it will be realized in the next 5-10 years or if it's just false hope. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
community Natural methods of reversing MPB
The conversation discusses natural methods for addressing male pattern baldness, with the original poster using a plant-based diet, herbs, scalp massages, pumpkin seed oil, and dermapen treatments, while avoiding pharmaceuticals like minoxidil and finasteride due to concerns about side effects. Other users suggest that pharmaceuticals like finasteride may be necessary for significant hair loss, but the original poster remains committed to natural approaches.