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      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 1 year ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

      in Progress Pictures  16 upvotes 2 months ago
      The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

      community How to overcome baldness with finasteride allergy

      in Chat  5 upvotes 3 months ago
      The conversation discusses alternatives for hair loss treatment for someone allergic to finasteride, suggesting options like hair systems, topical anti-androgens such as CB-03-01, RU58841, and kx-826. It highlights the challenges faced by individuals allergic to anti-androgen inhibitors and the need for more information on this topic.

      community Most promising cures for baldness as of May 2026

      in Treatment  56 upvotes 1 month ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community I think the hairloss finally delivered me a depression

       19 upvotes 7 years ago
      User struggles with hair loss after 2.5 years on minoxidil and 1 year on finasteride, feeling depressed. Replies suggest accepting the situation and not focusing on baldness in public.

      community 2 months of topical minoxidil (5%) use and there is a shadow now!

      in Transgender  192 upvotes 2 years ago
      The post discusses the user's experience with topical minoxidil (5%) for hair loss, showing some improvement after 2 months. Suggestions from others include keeping the hair shorter on the sides and back, adding finasteride for better results, and considering a shaved head look, though the latter was debated for its femininity.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.
      Trying to identify area of treatment with topical fin

      community Trying to identify area of treatment with topical fin

      in General  136 upvotes 6 months ago
      The user is considering using topical finasteride for thinning hair around the middle part, vertex, and crown, and is unsure if the whole scalp is thinning. Another user suggests oral finasteride is more effective than topical, and recommends consulting a dermatologist for proper treatment.

      community Balding, stressed and depressed

      in Chat  63 upvotes 3 years ago
      A 22 year old man who is experiencing hair loss, thinning and dry scalp, has tried treatments such as finasteride and minoxidil, and other users sharing their experiences with similar issues.

      community Hair won't regrow (even outside of MPB areas)

      in Treatment  6 upvotes 1 year ago
      User experiences slow hair regrowth despite using finasteride, topical minoxidil, and supplements like biotin, zinc, and collagen. They seek advice on addressing overall slow hair regrowth.

      community Hair journey since august, help!

      in Is this regrowth?  22 upvotes 1 year ago
      The conversation is about hair loss and treatments, with suggestions to use finasteride or dutasteride as DHT blockers and minoxidil for regrowth. Oils and shampoos are considered ineffective for androgenic alopecia without these medications.

      community Hair loss recover with topical Fin/Min treatment.

      in Is this regrowth?  7 upvotes 1 year ago
      A 42-year-old male experienced hair regrowth using a topical treatment of finasteride, ketoconazole, and minoxidil, noticing increased hair density and reduced hair loss over a year. He plans to switch to oral finasteride and continue using topical minoxidil, with a dermatologist's guidance.

      community Coffee and androgenetic alopecia

      in Research/Science  11 upvotes 3 years ago
      The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.

      community From hairline recession to full-blown resurrection

      in Satire  75 upvotes 2 months ago
      The conversation humorously discusses hair loss and its treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a transformation from hairline recession to significant hair regrowth.

      community How I started reversing Male Pattern Baldness naturally ?

      in Question  7 upvotes 9 years ago
      The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

      community My somewhat nuclear Hair loss prevention procotocol

      in Treatment  6 upvotes 2 years ago
      A 21-year-old male shared his extensive hair loss treatment protocol, which includes Dutasteride, RU58841, Ketoconazole shampoo, oral Minoxidil, pyrilutamide, MK677, dermastamping, and castor oil, and reported improved hair regrowth and overall well-being. He has experienced no side effects and has also improved his diet and lifestyle.

      community What to do... what to do...

       6 upvotes 9 years ago
      A mid-30s individual is experiencing hair loss at the front and temples but not the crown, and is seeking affordable treatments. They have ordered pumpkin seed oil capsules due to cost and side effects concerns with official treatments.

      community 31M with AGA + seb derm: worried I’m late to start finasteride — start now or control scalp first?

      in Basic Questions  102 upvotes 5 days ago
      A 31-year-old male with androgenetic alopecia and seborrheic dermatitis is considering starting finasteride and minoxidil for hair loss, while also using ketoconazole and salicylic acid shampoos for scalp treatment. He is concerned about the timing of starting finasteride and potential side effects, and seeks advice on whether to prioritize scalp health or begin hair loss treatments simultaneously.

      community What are these spots on my scalp

      in Treatment  51 upvotes 1 year ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community Scalp pain, diffuse thinning and Fin+nizoral

      in Chat  7 upvotes 2 years ago
      A user experiencing scalp pain and diffuse hair thinning is taking finasteride and using Nizoral shampoo. They plan to continue finasteride for 6 months and consider adding minoxidil if no improvement is seen.