Amplifica starting clinical trials for new hairloss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.
PP405 is a new hairloss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
The user regrets their hair transplant after 5 months due to patchy and thin hair, despite starting finasteride at the same time. Many recommend waiting 12-18 months for results and using finasteride and minoxidil before and after the transplant.
The user plans to stop finasteride after three months, believing hairloss isn't due to DHT, and will continue with oral minoxidil, microneedling, and ketoconazole shampoo. They suspect stress and poor nutrition are the main causes and seek opinions on DHT blockers' effectiveness.
A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hairloss is now experiencing unusual hairloss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.
User shared progress in treating hairloss and improving skin, using treatments like finasteride, minoxidil, RU58841, tretinoin, microneedling, and skin care regimen. Others commented on the impressive results and asked about costs and side effects.
The conversation discusses a small patch of missing hair and whether treatments like Minoxidil, finasteride, or RU58841 could help. The user is seeking advice on addressing this specific hair issue.
Dutasteride is unlikely to worsen hairloss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.
A user shared their experience with hairloss treatments, including RU58841, ketoconazole shampoo, caffeine shampoo, and topical finasteride. They found RU58841 effective for diffuse thinning but experienced severe hairloss after stopping it; topical finasteride worked well for a receding hairline but caused side effects. They also use a charcoal shampoo and practice scalp massages.
Kitchen_Plastic_2847 had been fighting hairloss since 2019-2020 and was initially successful in regrowing his hair with finasteride. However, after contracting Covid three times back to back at the start of 2021, he started to lose his hair again. He found a new dermatologist who prescribed him oral minoxidil along with finasteride, but eventually decided it wasn't worth spending all the money to try and save his hair.
Finasteride and dutasteride are discussed as preventative treatments for hairloss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hairloss.
The user shared their 10-year hairloss journey, discussing treatments like oral minoxidil, oral finasteride, and LLLT, and ultimately deciding on a hair transplant. They also explored the possibility of having alopecia areata incognita and advised seeking multiple opinions before surgery.
A 20-year-old is dealing with hairloss, using finasteride and oral minoxidil, and considering dutasteride. Others suggest treatments like dutasteride, hair transplants, therapy, and lifestyle changes to boost confidence and mental health.
There is no natural way to stop hairloss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.
A 57-year-old man with severe hairloss since age 14 tried various hairloss treatments over two years, including finasteride, dutasteride, minoxidil, and supplements, with some minor regrowth. He also experimented with topical treatments and microneedling, but results were not cosmetically significant.
The user is considering whether to delay meeting their long-distance girlfriend to undergo a hair transplant or meet her with their current hairloss, having used Dutasteride, Pyrilutamide, and Minoxidil. Most responses advise being honest about the hairloss, suggesting confidence and authenticity are more important than appearance.
A user underwent a hair transplant with 3500 grafts at WSC clinic in Istanbul and uses finasteride, biotin, multivitamins, minoxidil with finasteride, biotin shampoo, and coconut oil with peppermint oil for hairloss treatment. Another user commented that the result looks like a barren patch of hair.
A 26-year-old man embraced baldness, gaining confidence and personal growth, and encourages self-acceptance. Others discussed hairloss treatments like Minoxidil and finasteride, but he did not use them.
A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hairloss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.
Prolactin and cortisol are identified as key factors in hairloss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.
The user has been using topical Minoxidil and oral Finasteride for 6 months to treat hairloss, with noticeable improvement. Another user mentioned using unnamed drops for 4 months to successfully reduce a bald patch, but with less effect on a receding hairline.
User frustrated with lack of results from finasteride and minoxidil for hairloss. Others suggest checking for other health issues, focusing on fitness, and considering alternative treatments.
A user shared progress pictures after 9 months of using Propecia and minoxidil for hairloss, emphasizing that hairloss is not a problem. Another user commented on their own use of finasteride and minoxidil, noting no side effects.
A 25-year-old woman has been losing hair for 10 years despite normal thyroid, hormone levels, and B12 supplementation. She has used Minoxidil with limited success and is considering hair transplants, Propecia, or shaving her head and wearing wigs.
A user takes 5mg oral minoxidil, oral dutasteride, topical tretinoin, stemoxydine, topical minoxidil, and uses dermarolling for hairloss but sees less impressive, patchy regrowth compared to others. Another person suggests some online results may be enhanced with hair fibers, not just medication.
Hairloss advice: get a shorter haircut and use hair building fibers like Toppik to improve appearance. User on big 4 treatments: Minoxidil, dermapen, Nizoral, and finasteride.
Hairloss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.
Hairloss treatments, specifically finasteride and minoxidil, being used by wealthy individuals to combat their genetic predisposition to baldness. It also discussed other potential treatments such as RU58841 and dutasteride.
The user is experiencing hairloss despite using finasteride, minoxidil, and needling since March. They suspect needling too deeply might be an issue and have adjusted the depth recently.