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      community Why so much hate for PP405 all of a sudden?

      in Technology  48 upvotes 10 months ago
      PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 1 month ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community A scary individual report of RU58841.

      in Research/Science  33 upvotes 1 year ago
      RU58841 caused severe side effects like heart palpitations and shortness of breath, leading the user to stop using it. Minoxidil and finasteride were effective without side effects, while RU58841's safety and effectiveness remain uncertain.

      community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

      in Treatment  22 upvotes 2 years ago
      Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

      community Koreabeautics V2 Microneedling Scam in Reddit

      in Microneedling  38 upvotes 1 year ago
      A user warns against buying the Koreabeautics V2 microneedling pen, claiming it's marketed through fake success stories and is overpriced. Another user shares their experience, acknowledging the pen's quality but agreeing it's too expensive and reliant on frequent needle head replacements.

      community Been diagnosed with mpb and acute TE

      in Chat  2 upvotes 8 months ago
      A 21-year-old male diagnosed with telogen effluvium and male pattern baldness started taking finasteride, which initially slowed hair shedding and slightly thickened hair. The doctor recommended iron and vitamin D supplements, and the user is considering minoxidil but wants to stabilize shedding first.

      community Has anyone gotten pp405 on the grey market yet?

      in Research/Science  10 upvotes 2 months ago
      People are discussing the use of an untested hair loss treatment called PP405, which is not available on the grey market. Some users are trying a mimic formulation called HP3, reporting thicker hair but no new growth yet.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  44 upvotes 1 month ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.

      community Self-Experiment - Topical Rapamycin or a-KB

      in Treatment  4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community Help labing up hair preservations

      in Research/Science 2 years ago
      The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 3 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community Replicel, worthy of hype or probable disappointment? Questions thread

       5 upvotes 9 years ago
      The conversation discusses the potential of Replicel/Shiseido treatment for hair loss, questioning its effectiveness, whether it grows new follicles, and its market release timeline. It also compares Replicel to other competitors like Kyocera/RIKEN/Tsuji.

      community HMI-115 question about potential earliest access

      in Research/Science  10 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community Is pp405 actually the cure ? Just how exciting is it ?

      in Research/Science  36 upvotes 6 months ago
      PP405 is a promising hair growth stimulant but not a cure for advanced hair loss, as it may only help dormant follicles. Treatments like Minoxidil, Finasteride, and Dutasteride are discussed, with emphasis on early intervention for effectiveness.

      community This sub is very toxic towards people who don’t blindly follow the fin mafia

      in Treatment  226 upvotes 2 years ago
      The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.