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      community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

      in Minoxidil  37 upvotes 7 years ago
      Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 2 months ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community Alcohol-free minoxidil available in Europe

      in Minoxidil  5 upvotes 4 months ago
      Alcohol-free minoxidil options in Europe, particularly from a German pharmacy, are recommended for those with seborrheic dermatitis. Users suggest alternatives like Alopexy and Doppelherz foam, and emphasize avoiding propylene glycol and alcohol to reduce irritation.

      community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

      in Research/Science  5 upvotes 9 months ago
      Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  335 upvotes 9 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community Started topical minoxidil 3 months ago (progress?)

      in Is this regrowth?  149 upvotes 1 year ago
      The user started using topical minoxidil and derma stamping for hair regrowth, along with multivitamins, biotin, and saw palmetto. Many suggest adding finasteride for better long-term results, but the user is hesitant due to potential side effects.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  60 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Does dutasteride stop hair loss forever?

      in Finasteride/Dutasteride  38 upvotes 1 year ago
      Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 1 year ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Finasteride + topical melatonin + rosemary oil for regrowth

      in Treatment  1 upvotes 1 year ago
      The user has been using finasteride for 4 months with positive results, including thicker and darker hair. They are seeking advice on maximizing hair growth without minoxidil, using a routine that includes finasteride, rosemary oil, argan oil, topical melatonin, specialized shampoos, and vitamins.

      community Dutasteride RAISES LIBIDO!

      in Treatments  222 upvotes 1 year ago
      Dutasteride can significantly increase libido, more so than finasteride. Users reported higher libido when switching from finasteride to dutasteride.

      community Expectations control for SCUBE3

      in Research/Science  20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Potential Cure?! Verteporfin- unlimited HT

      in Research/Science  44 upvotes 2 years ago
      The conversation discusses verteporfin as a potential treatment for hair regeneration, which could lead to unlimited hair transplants by healing the donor area. Some users are considering using verteporfin now, while others are hopeful it will be available for future hair transplants.

      community Verterporfin combined with hairline lowering?

      in Technology  7 upvotes 2 years ago
      Verteporfin might be a potential cure for hair loss and could heal scars, which may lead to natural-looking results when combined with hairline lowering surgery. One person suggests waiting to see if verteporfin actually works as claimed.

      community Can finasteride affect on your muscle and other things?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The conversation discusses using finasteride topically for hair loss and concerns about potential side effects like feminization and impact on muscle growth. One person shared their experience with finasteride, indicating it increased testosterone and did not prevent them from gaining muscle or strength.

      community Sublingual Minoxidil - Cure to Hairloss?

      in Minoxidil  583 upvotes 2 years ago
      The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

      community 9+ months progress pics and regimen details

      in Progress Pictures  13 upvotes 2 years ago
      The user shared a 9+ month hair loss treatment progress with 1mg finasteride in the morning, 2.5mg oral minoxidil at night, and vitamin A spray at night, noting the importance of seeing a dermatologist early as their cousin started treatment too late for it to be effective.

      community microneedling, do the gains go away?

      in Microneedling  23 upvotes 3 years ago
      Microneedling promotes hair growth by increasing circulation and collagen production, with gains potentially lasting longer than those from minoxidil. Some users report sustained results after stopping microneedling, unlike with minoxidil and finasteride.

      community What is fluridil binding affinity?

      in Treatment  4 upvotes 4 years ago
      Fluridil is hard to obtain and only available in Slovakia and Czechia, with no systemic side effects but possibly limited effectiveness compared to finasteride. The original poster is using finasteride and minoxidil without success and is considering trying fluridil despite its cost.

      community Whats the safety Profile for Breezula?

      in Treatment  6 upvotes 4 years ago
      The conversation is about the safety of Breezula compared to RU58841 for hair loss treatment. The user believes Breezula is safer but less effective than RU58841.

      community Best way to include peppermint oil into the routine?

      in Treatment  7 upvotes 4 years ago
      The conversation discusses incorporating peppermint oil into a hair loss treatment routine alongside minoxidil and possibly considering other second line options before using peppermint oil. Some people apply peppermint oil after minoxidil's absorption period or use shampoos containing peppermint oil.

      community Topical melatonin/oral

      in Research/Science  12 upvotes 5 years ago
      The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 5 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )

      in Treatment  3 upvotes 6 years ago
      The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.

      community When is Breezula expected to be available for the public?

      in Question  29 upvotes 7 years ago
      The conversation is about the availability of Breezula, a hair loss treatment, with speculation it might be released in 2022 or potentially never, as it's more effective than finasteride. No specific treatments were confirmed.