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      community There is news from pyrilutamide?

      in Product  32 upvotes 2 years ago
      The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

      community 4 1/2 months of Dut and Oral Min Update

      in Update  374 upvotes 4 months ago
      Significant hair regrowth was achieved after 4.5 months using 0.5 mg Dutasteride and 5 mg oral Minoxidil. Tips on obtaining prescriptions and discussions on effectiveness and side effects were also shared.

      community 100 days on fin+min+dermastamp

      in Progress Pictures  49 upvotes 1 month ago
      A user shared progress pictures after 100 days of using finasteride, topical minoxidil, and dermastamping, with oral minoxidil added two weeks ago, reporting no side effects. Some users praised the results, while others questioned the effectiveness of dermastamping and the visibility of hair growth.

      community Finasteride 1mg daily vs 1.25mg EOD vs 1.25mg 5 days a week

      in Basic Questions  122 upvotes 1 month ago
      The user is treating male pattern baldness with oral minoxidil, ketoconazole, derma rolling, rosemary oil, and topical minoxidil, and is considering adding finasteride. They are debating between three finasteride dosing strategies: 1mg daily, 1.25mg every other day, or 1.25mg five days a week, focusing on efficacy, safety, and cost.

      community A positive thought rolling into Christmas

      in Research/Science  12 upvotes 5 months ago
      The conversation is optimistic about future hair loss treatments, highlighting Veradermics, Breezula, and PP405 as promising options expected by 2027-2028. The user expresses hope that these developments will prevent future generations from experiencing the same struggles with hair loss.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  50 upvotes 1 year ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Hair Loss Inflammation Prevention Stack

      in Research/Science  46 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community DUT Risk profile for having kids?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

      community About Pyrilutamide Phase II US Trial

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

      community Chlorine dioxide: An effective product?

      in Research/Science  4 upvotes 1 year ago
      Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.

      community 6 month update on DUT AND minoxidil

      in Progress Pictures  69 upvotes 1 year ago
      The user has been using a regimen of dutasteride (DUT) and topical minoxidil (1ml once a day) for six months, resulting in hair regrowth and increased thickness. The user reports no side effects and mentions that the shedding phase lasted about a month.

      community 8 Weeks Progress. DUT and topical MIN

      in Progress Pictures  158 upvotes 10 months ago
      The user shared their 8-week hair regrowth progress using 0.5mg dutasteride, twice-daily topical minoxidil, and weekly 1.5mm microneedling. They noted visible improvement, though some users suggested reducing microneedling depth to avoid potential scalp damage.

      community 3 month progress - Oral min dut

      in Progress Pictures  12 upvotes 2 years ago
      The conversation is about someone's 3-month hair regrowth progress using 5mg oral minoxidil and 0.5mg dutasteride daily, with visible improvement noted.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Dutasteride 0.5 ED. 3 Months (INSANE REGROWTH)

      in Progress Pictures  19 upvotes 1 year ago
      Dutasteride 0.5mg daily led to significant hair regrowth in 3 months, with minimal side effects like slight pelvic pain and increased libido. The user switched from Finasteride to Dutasteride, noticing reduced hair shedding and improved hair condition.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 9 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 1 year ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Dht normal after taking fin and then dut

      in Treatment  2 upvotes 1 year ago
      The user has been taking dutasteride for 8 months and finasteride before that, with normal DHT levels but high estradiol and prolactin, leading to sexual side effects. The user is disappointed with these results.

      community Does anyone have experience with topical dut?

      in Finasteride/Dutasteride  7 upvotes 3 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.

      community at what point does RCP no longer benefit?

      in Treatment  5 upvotes 1 year ago
      A user is using Minoxidil, finasteride, saw palmetto, and Minimalist RCP serum to address hair thinning, with some success but concerns about the long-term benefits of Minimalist. They plan to continue Minoxidil and finasteride for another year before considering a hair transplant.