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      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  335 upvotes 9 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community 3 months on dut every other day min 3 times a week

      in Is this regrowth?  28 upvotes 11 months ago
      The user experienced hair regrowth and healthier hair after switching from finasteride to dutasteride, using it every other day along with minoxidil three times a week. They reported initial shedding but no side effects, and others in the conversation shared similar experiences or considered switching treatments.

      community A Short Recap on PP405 and AAD 2026

      in Update 1 week ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community 4 month progress .5mg dut + 2.5mg min

      in Is this regrowth?  100 upvotes 3 weeks ago
      A user shared their 4-month hair regrowth progress using 0.5mg dutasteride and 2.5mg minoxidil, reporting no side effects and significant improvement. The conversation includes discussions on treatment choices, dosages, and personal experiences with hair loss treatments.

      community My summation of PP405 - looks promising

      in Research/Science  210 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Transition protocols from fin to dut

      in Chat  2 upvotes 1 month ago
      Transitioning from finasteride to dutasteride for hair loss, with suggestions to either slowly transition or frontload dutasteride. The user is also using minoxidil, nizoral, needling, and LLLT.

      community Anybody try Duderma from min max?

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      A user is using topical dutasteride, topical finasteride, and minoxidil to address a receding hairline and is seeking opinions on their routine. They report seeing vellus hair growth after nearly three months of use.

      community Hey brothers, this post is about my clinical depression with mpd

      in Update  8 upvotes 2 years ago
      A 21-year-old experiencing hair loss and depression is planning to start finasteride treatment and is asking for others' experiences. Another user responds positively, stating that finasteride has helped alleviate their depression caused by hair loss.

      community Dht normal after taking fin and then dut

      in Treatment  2 upvotes 1 year ago
      The user has been taking dutasteride for 8 months and finasteride before that, with normal DHT levels but high estradiol and prolactin, leading to sexual side effects. The user is disappointed with these results.

      community Sooo whens the next big thing gonna come?

      in Chat  16 upvotes 5 days ago
      New hair loss treatments like VDPHL01, PP405, Gt20029, and Breezula are anticipated, with VDPHL01 possibly releasing in 2027/28. Current treatments include finasteride, dutasteride, and minoxidil, but new options are eagerly awaited.

      community Can dutasteride keep RU or Pyrilutamide gains?

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      The conversation discusses whether hair gained from using Pyrilutamide or RU58841 can be maintained with dutasteride if the former treatments are discontinued. The user prefers oral minoxidil for its effectiveness and convenience over topical applications.

      community Veradermics VDPHL01: why isn’t anyone talking about it?

      in Treatment  44 upvotes 1 year ago
      Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

      community 8 Weeks Progress. DUT and topical MIN

      in Progress Pictures  158 upvotes 8 months ago
      The user shared their 8-week hair regrowth progress using 0.5mg dutasteride, twice-daily topical minoxidil, and weekly 1.5mm microneedling. They noted visible improvement, though some users suggested reducing microneedling depth to avoid potential scalp damage.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  32 upvotes 9 months ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community PP405 Phase 2a press release with early results

      in Research/Science  695 upvotes 9 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community a topical that combines MIN, FIN and DUT

      in Minoxidil  4 upvotes 3 years ago
      A user discusses a topical treatment combining Minoxidil, Betamethasone Valerate, Canrenone, Finasteride, and Dutasteride for hair loss. The treatment is RX-only and provided by a dermatologist.

      community Is PP405 formula available in grey market?

      in Treatment  16 upvotes 1 year ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.

      community 4 months progress / dut 0.5mg + topical min

      in Progress Pictures  108 upvotes 2 years ago
      The conversation is about someone's 4-month hair regrowth progress using 0.5mg dutasteride and topical minoxidil. Another person is inspired and is using 5mg finasteride and 5% minoxidil topically twice daily, hoping for similar results.