A user has been using dutasteride, RU58841, minoxidil, and ketoconazole for 2 years with no progress and worsening hair recession. They seek advice on how to proceed.
User experiencing hair loss on dutasteride; others suggest shedding is normal and to track progress with pictures. Some mention using RU58841 for improvement.
Combining finasteride with dutasteride may have additive benefits for reducing scalp DHT, but the extent is unknown. Some users report less shedding when using both treatments, with variations in dosage and application methods.
Exploring the potential of using Verteporfin to grow follicles in combination with microneedling, as well as the cost of administering a single injection and the possibility of combining it with minoxidil.
The user experienced significant hair shedding after using a dermapen at 1.5mm weekly, which they later realized was too much. They are now using a dermapen at 0.75mm weekly and are also using topical minoxidil twice daily and finasteride 1.25mg daily.
Switching from finasteride to dutasteride led to hair density loss, prompting consideration of returning to finasteride. Consistency with dutasteride and adding RU58841 did not prevent the loss, and users suggest giving dutasteride more time or consulting a dermatologist.
The user is experiencing a greasy and dandruff-prone scalp from using RU58841 with glycerin and is seeking alternative carriers for seborrheic dermatitis. They are also using dutasteride 0.5mg.
Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.
User shared a progress photo after 1.5 years of using 1mg Finasteride daily, 5% Minoxidil twice daily, Nizoral shampoo and conditioner 2-3 times weekly, and derma stamping bi-weekly. The post is categorized under "Progress Pictures."
User experienced scarring from microneedling at fast speed and paused treatment for 3-4 weeks to recover. Advice given includes waiting a full month for recovery to avoid scars.
A 39-year-old user experienced hair regrowth using oral dutasteride, oral minoxidil, dermastamping, and Nizoral shampoo after switching from finasteride and topical minoxidil. They are hopeful for significant improvement in their receding hairline.
A user successfully reversed hair loss over 17 months using 0.5mg dutasteride and 5mg oral minoxidil daily, noting significant improvement without a transplant. Minor side effects like headaches and testicular discomfort were reported but resolved quickly.
The user is considering using "Grow Gorgeous Intense Hair Density Serum" alongside Minoxidil and is currently taking Finasteride. Some users doubt the serum's effectiveness, while others suggest it may help with hair strength and thickness, but opinions are mixed.
The conversation is about a user experiencing hair shedding after switching from finasteride to dutasteride and increasing their oral minoxidil dose. The user is advised to continue with the current treatment, consider adding topical minoxidil, and consult a dermatologist for potential underlying issues.
2-deoxy-D-ribose, a sugar molecule, is found to be 80%-90% as effective as Minoxidil in promoting hair growth, showing potential for alopecia treatment. Concerns include high cost, lack of human studies, and possible side effects like diarrhea and nausea.
Pelage Pharmaceuticals' PP405, a new hair loss treatment, was recognized by Time Magazine as one of the best inventions of 2025. The conversation expresses optimism about the recognition of this in-development treatment.
The conversation discusses combining oral dutasteride with topical finasteride to further reduce scalp DHT levels for hair regrowth. Users debate the effectiveness and safety of this combination, with some suggesting alternatives like topical antiandrogens such as RU58841, fluridil, and alfatradiol.
A user shared a two-year update on their hair loss treatment using dutasteride (0.5mg/day), minoxidil (Kirkland topical foam 2x/day), a 1.5mm derma roller every other week, and a daily multivitamin with biotin. They reported significant hair regrowth with no side effects, emphasizing the importance of consistency and a healthy lifestyle.
An individual in Italy used a fake prescription to obtain Dutasteride cheaply, suggesting others do the same to avoid high costs. They discuss the effectiveness and side effects of Dutasteride compared to Finasteride for hair loss, with some users considering switching due to better tolerance.
The conversation is about a user's nearly 4-month hair loss treatment regimen, which includes dutasteride every other day, 0.25ml minoxidil on the hairline once a day, and using a 1.5 mm derma stamp every two weeks. Some responses question the need to start multiple treatments simultaneously, while others comment on the visible improvement and the necessity to continue treatment for sustained results.
A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.
A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.
Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.
A user's hair loss treatment progress over the last 6 months using finasteride, minoxidil and dermarolling; other users have commented to ask questions or share their own experiences.
The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.
The user discovered their previous hair loss medication was counterfeit and switched to Propecia, which significantly lowered their DHT levels. They plan to continue using Propecia and add oral Minoxidil to their routine for better results.
The conversation discusses a video about hair shedding related to finasteride and dutasteride, with some users debating the credibility of non-professional sources. The video is praised for compiling work by doctors and researchers, despite some users preferring content from licensed medical professionals.