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750-780 / 1000+ resultscommunity 3α-Hydroxysteroid dehydrogenase community driven study, not anytime soon guys.
High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.
community REMINDER: you can get your prescriptions medications transferred to other pharmacies.
community My Fluridil/Eucapil 2% experience 30 days.
community Alpicort E: Diffuse thinning/MPB medication, Can't find much info on it?
A user was prescribed Alpicort E, which contains Estradiol Benzoate, Prednisone, and Salicylic Acid, for hair loss and is seeking others' experiences due to concerns about potential side effects.
community Pyrilutamide: Increased libido. Anyone else experienced something similar with either RU or Pyri?
An increase in libido associated with the use of Pyri, and a discussion about how it may be working comparably to other hair loss treatments such as RU58841, Finasteride and Minoxidil.
community second shed on dutasteride, but a woman
A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.
community NW4 -> NW 2.5 (1yr progress) RU 8.5-9% ED and topical Dut .1% + RU 5% 1.5x a week. (+ caffeine redensyl scalp treatment ED)
The conversation discusses hair regrowth progress from Norwood scale 4 to 2.5 over a year using daily 8.5-9% RU58841, topical Dutasteride 0.1%, RU58841 5% 1.5 times a week, and daily caffeine redensyl scalp treatment.
community Density loss after 4 months on DUTASTERIDE, does it get better if you stick with it?
A user experienced increased hair density loss after 4 months on dutasteride combined with finasteride. They are also using topical dutasteride with azelaic acid and alfatradiol but cannot tolerate antiandrogens like RU58841 due to headaches.
community EveryChem 3HP / PP30 page data vs NMR PDFs in their website : metadata mistake or document mismatch?
There is an inconsistency between the molecular weight and formula listed on EveryChem's product page and the analytical PDFs for 3HP and PP30, suggesting a possible error in the product description. Concerns are raised about EveryChem's business practices and lack of transparency in testing and manufacturing.
community What's your thoughts on Pyrilutamide
The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.
community 2 years on fin only :) EOD. No sides.
A user shared their 2-year progress using finasteride every other day with no side effects. Others discussed their experiences, shedding cycles, and patience with the treatment.
community platelet rich plasma experiences/thoughts?
Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.
community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell
community (1 month pyrilutamide results) what I noticed: massive shedding phase around week 2. it was worse than finasteride and minoxidil shedding. no side effects other than headache the first time I applied it. I feel like it's working but still too soon to tell.
The user experienced significant hair shedding in the second week of using pyrilutamide, more so than with finasteride and minoxidil, and reported a headache after the first application. They believe the treatment may be working but acknowledge it's too early to confirm results.
community 6 Month Progress Pics - Dutasteride
The conversation discusses hair loss and the use of Dutasteride for treatment. One participant strongly supports the use of Dutasteride.
community Stay on Fin and add Pyrilutamide vs transition to Dut and no Pyri?
User is considering switching from finasteride to dutasteride and adding pyrilutamide for hair loss treatment. Other users recommend dutasteride for its effectiveness and suggest adding pyrilutamide.
community 4 years ago (top) vs today (bottom) 1mg Finasteride daily
community LPT: Sebhorric Detmatitis Treatment
Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.
community A reasonably reputable guy claims that he has reversed his hairloss. Could be an interesting read.
A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.
community Starting my Pyrilutamide + ru58841 journey
An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.
community Seeking advice from dut non-responders who used RU
The conversation discusses hair loss treatments, specifically the use of RU58841 by individuals who did not respond to dutasteride. Users share experiences with maintaining hair using RU58841 and mention trying pyrilutamide and the upcoming availability of pp405.
community Progress - one year with fin 1mg (oral) and min 5% foam (topical)
community 21M with a nasty case of MPB; Heres what's on my radar for the future.
Hopeful treatments for hair loss, including Verteporfin, Androgen Receptor Degradation, and SCUBE3. These treatments offer potential solutions to slow or stop the effects of androgens on the scalp.
community If PP405 does revive "dead" hair follicles would DHT blockers theoretically be enough to maintain that new hair
PP405 may revive dormant hair follicles, and DHT blockers like finasteride or dutasteride could maintain new hair. Combining PP405 with minoxidil might be optimal, but long-term effects and continuous use are uncertain.
community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.
The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.
community 11 months on oral .25 min and .5 dut
community PSA: My GP told me you should get yearly kidney and liver tests if you are on Dutasteride
Dutasteride users should get yearly kidney and liver tests, especially young people. General health checkups are not common in the UK, but such tests are recommended as a precaution.
community [Research] RU-58841/Pyrilutamide and impacts on male fertility
The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.