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      community Will I be a good candidate for Finasteride?

      in Chat 5 years ago
      A 17-year-old is considering finasteride for hair loss but is advised to wait due to potential hormonal effects at a young age. Alternatives like minoxidil, micro-needling, vitamins, and lifestyle changes are suggested instead.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  33 upvotes 3 months ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community The cure we've been ignoring: Anal Dutasteride

      in Satire  224 upvotes 1 month ago
      The conversation humorously discusses using anal administration of Dutasteride as a novel method for treating hair loss, suggesting it could target DHT production more effectively. It includes satirical comments about the method's potential effects and absurd outcomes.

      community Regimen proposal (incl. dut meso) (event industry)

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community How many years can we expect PP405 to be on the market

      in Product  12 upvotes 10 months ago
      PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.

      community Dutasteride Mesotherapy in NJ or PA

      in Treatment  6 upvotes 2 years ago
      A user is seeking recommendations for doctors who perform Dutasteride mesotherapy in NJ or PA, as they are having trouble finding one through Google. The conversation focuses on finding a suitable provider for this specific hair loss treatment.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Watching my younger brother bald hurts so much.

      in Treatment  268 upvotes 1 year ago
      A 19-year-old is distressed about his 17-year-old autistic brother's hair loss, projecting his own insecurities despite being on finasteride and dutasteride. Replies suggest the brother might not care about balding, and the poster should address his own issues.

      community Sources for peptides and Dut/Fin

      in Treatment  1 upvotes 3 months ago
      The user is seeking advice on sourcing finasteride, dutasteride, and minoxidil, as their doctors are unwilling to prescribe both finasteride/dutasteride and minoxidil simultaneously. They are also looking for sources of GHK-Cu and RU58841 in the USA, with suggestions including using services like Hims, ro.co, and Musely.

      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 7 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community Lemon aid health Prescription for finasteride

      in Product  2 upvotes 1 year ago
      The conversation is about obtaining a finasteride prescription through Lemon Aid Health. The user is exploring the process and alternatives for getting the prescription sent to a pharmacy.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  460 upvotes 9 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community How dangerous would fin be for me to take at 18?

      in Finasteride/Dutasteride  27 upvotes 2 years ago
      An 18-year-old has been using topical finasteride and minoxidil for hair loss without noticeable improvement and is considering oral finasteride. Some users suggest starting oral finasteride at 18 is fine, especially if puberty is complete, while others recommend caution and consulting a specialist.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 2 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.