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      community Anyone tried topical adenosine?

      in Product  4 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  112 upvotes 11 months ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community 7 Month Hair Progress (0.5 mg dut only, diffuse thinning)

      in Progress Pictures  716 upvotes 2 years ago
      An 18-year-old male switched from topical finasteride and minoxidil to oral dutasteride for diffuse hair loss and saw improvement without side effects, despite experiencing scalp itch and shedding. Commenters noted significant hair regrowth and were surprised by his young age and appearance.

      community Anyone on meds on TRT or gear??

      in Research/Science  3 upvotes 8 months ago
      The conversation discusses the use of TRT, dutasteride, minoxidil, and potentially RU58841 for hair loss. Concerns about the risk of developing Cutis verticis gyrata with minoxidil and TRT are raised.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Wednesday after micro needling through Friday today.

      in Treatment  1 upvotes 1 year ago
      The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  14 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Scarring Alopecia and NSAIDs?

      in Female  3 upvotes 5 years ago
      The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

      community Dutasteride and anal with partner

      in Satire  119 upvotes 2 weeks ago
      Using dutasteride anally as a hair loss treatment, with humorous and satirical comments on its effects and implications.

      community Should I start taking finasteride at 17.5? (M)

      in Finasteride/Dutasteride  4 upvotes 8 months ago
      A 17-year-old is experiencing hair thinning and is using minoxidil, ketoconazole shampoo, saw palmetto, and pumpkin seed oil. They are considering starting finasteride but are concerned about its effects on development and are seeking advice on whether to proceed with finasteride or switch to oral minoxidil.

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 7 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community PP405 could be released before GTA 6

      in Chat  133 upvotes 4 months ago
      PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.

      community 17 months dut + min + 2800 grafts (5 months)

      in Progress Pictures  80 upvotes 10 months ago
      The user shared progress on hair restoration using dutasteride, oral minoxidil, and 2800 grafts, noting significant improvement in hair thickness and coverage. They discussed the importance of continuing DHT blockers like finasteride or dutasteride post-transplant to prevent further hair thinning.

      community Switching to minoxidil and tretinoin from just minoxidil

      in Minoxidil  6 upvotes 1 year ago
      The user is considering switching from a 5% minoxidil and 0.1% finasteride mix to a combination of 5% minoxidil, 0.1% finasteride, 0.01% tretinoin, and 1.5% azelaic acid due to low regrowth success. They are seeking advice on whether to use the new mix at night and continue the old mix in the morning or try oral minoxidil in the morning.

      community How to get finestride presciption

      in Finasteride/Dutasteride  2 upvotes 1 week ago
      An 18-year-old experiencing hair loss seeks a finasteride prescription but faces skepticism from doctors who only recommend vitamins. A suggestion is made to consult a dermatologist for a proper diagnosis and potential treatment with finasteride or minoxidil.

      community New article on PP405..........

      in Research/Science  109 upvotes 11 months ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community is Oleanic acid a DHT blocker ?

      in Treatment  4 upvotes 1 year ago
      A user is experiencing hair thinning and is using a peptide with oleanic acid as a DHT blocker, along with minoxidil, while waiting for topical finasteride. They plan to use a combination of minoxidil, finasteride, dermastamp, ketoconazole, and scalp massages, but are advised to stick to proven treatments like finasteride and minoxidil.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Pp405 full presentation on new topical

      in Product  108 upvotes 3 weeks ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community 7 month progress check-in (fin/min)

      in Is this regrowth?  9 upvotes 7 months ago
      A 19-year-old is using minoxidil, finasteride, tretinoin, caffeine, and oils for hair regrowth, with positive results and no side effects. They are considering increasing finasteride dosage and possibly switching to dutasteride in the future.