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      community Finasteride - discomfort pelvir/urethra

      in Finasteride  79 upvotes 1 year ago
      Finasteride can cause pelvic or urethral discomfort for some users. Reducing the dose to 0.25 mg on Mondays, Wednesdays, and Fridays is being considered as a potential solution.

      community Pyrilutamide from Ligand Chem in the UK

      in Research/Science  4 upvotes 3 years ago
      Pyrilutamide from Ligand Chem was used by several individuals to address hair loss, with mixed results and no significant side effects reported. Some users switched to Minoxidil Max for better value, while others noted no hair growth or only a reduction in shedding.

      community 2 Month Progress (Fin 1mg and Min( 2.5mg)

      in Update  105 upvotes 10 months ago
      The user is happy with their 2-month progress using a 3-in-1 oral tablet containing finasteride, minoxidil, and biotin, with minor side effects like slightly lower libido. They report no significant issues like breakouts and note that oral treatments are more effective than topical ones.

      community Is hair cloning and setipiprant coming in 2020?

      in Question  5 upvotes 9 years ago
      The conversation discusses potential hair loss treatments, including hair cloning, setipiprant, and topical finasteride, questioning their availability and effectiveness as permanent cures. The user is inquiring about the release dates and efficacy of these treatments.

      community 10 weeks on pyrilutamide Update

      in Update  11 upvotes 3 years ago
      How combining minoxidil, finasteride and pyrilutamide has helped the user with hair loss. The user also acknowledges that it takes time to see any results and that minoxidil is necessary for stimulating new hair growth.

      community Finasteride only (1mg) for 5 months

      in Progress Pictures  139 upvotes 3 months ago
      The user has been using 1mg of finasteride daily for 5 months, noticing hair regrowth and thickening without significant side effects. They have not used minoxidil and plan to continue with finasteride before considering additional treatments.

      community Are there alternatives to finasteride?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about seeking alternatives to finasteride for hair loss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Anyone in Pyrilutamide currently?

      in Treatment  13 upvotes 3 years ago
      User considers trying Pyrilutamide for hair loss and itch relief. Another user shares positive experience with Pyrilutamide, no side effects.

      community Only finasteride 1.25 for 5 months

      in Progress Pictures  1046 upvotes 2 years ago
      The conversation is about a user's hair regrowth after using only finasteride for 5 months, with some users expressing congratulations and curiosity about the lack of minoxidil use and potential side effects.

      community Why is there so much negativity around pyrilutamide?

      in Research/Science  19 upvotes 1 year ago
      Pyrilutamide is discussed as an effective hair loss treatment by some users, despite skepticism due to limited data and underwhelming trial results. Users compare it to finasteride, minoxidil, and RU58841, with some expressing interest in its potential as an adjunct treatment.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 2 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

      in Treatment  27 upvotes 2 years ago
      The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

      community 11 months on fin + min. Thoughts?

      in Progress Pictures  918 upvotes 1 year ago
      A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

      community Verteporfin day 119 update - donor hair regeneration human trial

      in Research/Science  146 upvotes 3 years ago
      A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

      community RU58841 and Min - topical 50 mg each day

      in Progress Pictures  6 upvotes 2 years ago
      The conversation is about a person's hair improvement after 14.5 months using RU58841 and Minoxidil topically at 50 mg each day, with noticeable hairline improvement but incomplete crown area recovery. The person struggles to take good pictures of their crown area.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  120 upvotes 1 year ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

      community 5 months on Fin 1.25mg + Min 5% + Nizoral 2 x week

      in Progress Pictures  80 upvotes 2 years ago
      The conversation is about a user's successful hair regrowth after 5 months of using 1.25mg Finasteride, 5% Minoxidil, and Nizoral twice a week. The user, aged 28, experienced shedding in the first 6 weeks but has seen significant improvement since.

      community Pyrilutamide and RU alternatives?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community 6 months progress 1mg finasteride daily

      in Progress Pictures  310 upvotes 1 year ago
      The user experienced significant hair improvement using 1mg finasteride daily without side effects. They are advised to continue treatment to maintain results and consider cost-effective purchasing options.